1996
DOI: 10.1002/jmri.1880060503
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Comparison of dysprosium DTPA BMA and superparamagnetic iron oxide particles as susceptibility contrast agents for perfusion imaging of regional cerebral ischemia in the rat

Abstract: The aim of the study was to compare the first-passage profiles of dysprosium diethylenetriamine penta-acetic acid bis(methylamide) (DTPA BMA) and the superparamagnetic iron oxide particles NSR 0430 in regions with severe and moderate cerebral ischemia. In seven rats subjected to middle cerebral artery occlusion, two dynamic MR perfusion imaging series were acquired after intravenous bolus injections of .5 mmol/kg dysprosium DTPA BMA and .06 mmolFe/kg iron oxide particles, respectively. The doses were chosen to… Show more

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Cited by 29 publications
(13 citation statements)
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“…Abnormal signal changes were observed in all experimental rats after the middle cerebral artery was occluded with line embolism for 1 h. 4 were not significantly different between Groups A and B, which further supports our conclusions.…”
Section: Zhang Sx Et Al: Dsc-mr Perfusion Weighted Imaging and Rat Csupporting
confidence: 88%
See 4 more Smart Citations
“…Abnormal signal changes were observed in all experimental rats after the middle cerebral artery was occluded with line embolism for 1 h. 4 were not significantly different between Groups A and B, which further supports our conclusions.…”
Section: Zhang Sx Et Al: Dsc-mr Perfusion Weighted Imaging and Rat Csupporting
confidence: 88%
“…The rCBV, rMTT and TTP values of ROI 3 and ROI 4 from Groups A and B were not significantly different (p > 0.05). The rrCBV of Group A were 0.36 ± 0.08 and 0.61 ± 0.10, respectively, and those of Group B were 0.39 ± 0.08 and 0.63 ± 0.12, respectively.…”
Section: General Datamentioning
confidence: 79%
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