Comparison of ECG signals and arrhythmia detection using jacketed external telemetry and implanted telemetry in monkeys

Kremer, John J.; Foley, C. Michael; Xiang, Zhuzai; Lemke, Elizabeth; Sarazan, R. Dustan; Osinski, Mark A.; Beck, Thomas W.

doi:10.1016/j.vascn.2011.03.164

Cited by 7 publications

(7 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Hence, ECG in NHPs is either collected from sedated animals [ 6 , 8 , 9 ] or by implanting a telemetry device in combination with highly invasive intracorporal sensors [ 10 – 12 ]. For a non-invasive ECG acquisition from non-sedated monkeys a wearable jacket can be used [ 1 , 13 , 14 ], but this also requires extensive training and physical contact when preparing the animal, which may affect the physiological state.…”

Section: Introductionmentioning

confidence: 99%

Using imaging photoplethysmography for heart rate estimation in non-human primates

et al. 2018

View full text Add to dashboard Cite

For humans and for non-human primates heart rate is a reliable indicator of an individual’s current physiological state, with applications ranging from health checks to experimental studies of cognitive and emotional state. In humans, changes in the optical properties of the skin tissue correlated with cardiac cycles (imaging photoplethysmogram, iPPG) allow non-contact estimation of heart rate by its proxy, pulse rate. Yet, there is no established simple and non-invasive technique for pulse rate measurements in awake and behaving animals. Using iPPG, we here demonstrate that pulse rate in rhesus monkeys can be accurately estimated from facial videos. We computed iPPGs from eight color facial videos of four awake head-stabilized rhesus monkeys. Pulse rate estimated from iPPGs was in good agreement with reference data from a contact pulse-oximeter: the error of pulse rate estimation was below 5% of the individual average pulse rate in 83% of the epochs; the error was below 10% for 98% of the epochs. We conclude that iPPG allows non-invasive and non-contact estimation of pulse rate in non-human primates, which is useful for physiological studies and can be used toward welfare-assessment of non-human primates in research.

show abstract

Section: Introductionmentioning

confidence: 99%

Using imaging photoplethysmography for heart rate estimation in non-human primates

et al. 2018

View full text Add to dashboard Cite

show abstract

“…In monkeys, recording HR either involves ECG or PPG under sedation 18 – 20 or implanting a telemetry device for HR measure during behaviour 21 , 22 . PPG recording or HR measures using captors embedded in a wearable jacket is also an option 11 , 23 , 24 . However, this requires intensive monkey training and might bias HR measures due to discomfort or stress.…”

Section: Introductionmentioning

confidence: 99%

Automated video-based heart rate tracking for the anesthetized and behaving monkey

Froesel

Goudard

Hauser³

et al. 2020

Sci Rep

View full text Add to dashboard Cite

Heart rate (HR) is extremely valuable in the study of complex behaviours and their physiological correlates in non-human primates. However, collecting this information is often challenging, involving either invasive implants or tedious behavioural training. In the present study, we implement a Eulerian video magnification (EVM) heart tracking method in the macaque monkey combined with wavelet transform. This is based on a measure of image to image fluctuations in skin reflectance due to changes in blood influx. We show a strong temporal coherence and amplitude match between EVM-based heart tracking and ground truth ECG, from both color (RGB) and infrared (IR) videos, in anesthetized macaques, to a level comparable to what can be achieved in humans. We further show that this method allows to identify consistent HR changes following the presentation of conspecific emotional voices or faces. EVM is used to extract HR in humans but has never been applied to non-human primates. Video photoplethysmography allows to extract awake macaques HR from RGB videos. In contrast, our method allows to extract awake macaques HR from both RGB and IR videos and is particularly resilient to the head motion that can be observed in awake behaving monkeys. Overall, we believe that this method can be generalized as a tool to track HR of the awake behaving monkey, for ethological, behavioural, neuroscience or welfare purposes.

show abstract

“…Hence, ECG in NHPs is either collected from sedated animals [6,8,9] or by implanting a telemetry device in combination with highly invasive intracorporal sensors [10][11][12]. For a non-invasive ECG acquisition from non-sedated monkeys a wearable jacket can be used [1,13,14], but this also requires extensive training and physical contact when preparing the animal, which may affect the physiological state.…”

Section: Introductionmentioning

confidence: 99%

Using imaging photoplethysmography for heart rate estimation in non-human primates

Unakafov

Moeller

Kagan

et al. 2018

Preprint

View full text Add to dashboard Cite

For humans and for non-human primates heart rate is a reliable indicator of an individual's current physiological state, with applications ranging from health checks to experimental studies of cognitive and emotional state. In humans, changes in the optical properties of the skin tissue correlated with cardiac cycles (imaging photoplethysmogram, iPPG) allow non-contact estimation of heart rate by its proxy, pulse rate. Yet, there is no established simple and non-invasive technique for pulse rate measurements in awake and behaving animals. Using iPPG, we here demonstrate that pulse rate in rhesus monkeys can be accurately estimated from facial videos. We computed iPPGs from seven color facial videos of three awake head-stabilized rhesus monkeys. Pulse rate estimated from iPPGs was in good agreement with reference data from a pulse-oximeter with error of pulse rate estimation below 5% for 82% of all epochs, and below 10% for 98% of the epochs. We conclude that iPPG allows non-invasive and non-contact estimation of pulse rate in non-human primates, which is useful for physiological studies and can be used toward welfare-assessment of non-human primates in research.

show abstract

Comparison of ECG signals and arrhythmia detection using jacketed external telemetry and implanted telemetry in monkeys

Cited by 7 publications

References 0 publications

Using imaging photoplethysmography for heart rate estimation in non-human primates

Using imaging photoplethysmography for heart rate estimation in non-human primates

Automated video-based heart rate tracking for the anesthetized and behaving monkey

Using imaging photoplethysmography for heart rate estimation in non-human primates

Contact Info

Product

Resources

About