Comparison of effects of classic LMA, cobraPLA and V-gel rabbit on QTc interval

Abstract

AIM: We aimed to compare the effects of three different supraglottic airway devices, the classic LMA, PLA, and V-gel, on hemodynamics and QTc in rabbits under general anesthesia. METHOD: The rabbits were divided into four groups: Group C (n = 5) control group with no airway device used, Group L (n = 5, classic LMA), Group P (n = 5, CobraPLA) and Group V (n = 5, V-gel-rabbit). Basal values of heart rate (HR), mean arterial pressure (MAP) and ECG for QTc interval were measured and the measurements were evaluated at 1, 5, 15, and 30 minutes after inserting the airway device RESULTS: The values of HR, MAP and QTc in Group V at minutes 1 and 5 were signifi cantly different to those in Group L and Group P (p < 0.05). DISCUSSION: The classic-LMA and cobraPLA cover a wide part of the perilaryngeal area with cuffs infl ated to about 60 cmH 2 O of pressure resulting in mucosal compression. As V-gel rabbit does not have a cuff, it covers a smaller part of the laryngopharyngeal area, and thus does not cause mucosal compression, and the hemodynamic response is weaker. CONCLUSION: When comparing hemodynamic responses to other supraglottic airway devices, the response to V-gel rabbit is minimal and we consider that similar studies using the I-gel on humans are required (Fig. 5

Predictive risk factors of failed laryngeal mask airway insertion at first attempt

“…Lidocaine gel, as a common lubricant and surface anesthetic, is often used to lubricate the LMA and thus prevent and reduce the risk of pharyngeal complications after laryngeal mask anesthesia. 20 However, relevant studies do not support our conclusion and instead considered that the existing lubricants, including lidocaine gel, saline, and other medical lubricants, cannot effectively reduce the risk of pharyngeal complications. 21 , 22 In the current study, however, we confirmed that the use of lidocaine gel may significantly reduce the risk of first-attempt LMA insertion failure, which may help to reduce the risk of complications associated with delayed airway setting.…”

Investigation of histopathological effects after intra-arterial sugammadex injection in an experimental animal model

“…As described in a previous study, all animals had Rabbit V-gel ® inserted and oxygenation was supported with a mechanical ventilation device with respiration count held to 40/minute appropriate for rabbit physiology with a mix of 50 % oxygen and 50 % air for airway reliability (9). Body temperature was measured with a digital thermometer rectally inserted.…”