Comparison of efficacy and safety of postoperative treatment with loteprednol etabonate and bromfenac after phacoemulsification

Abstract

Aim: Comparison of efficacy and safety of loteprednol etabonate and bromfenac after phacoemulsification. Material and Methods: Multicenter prospective case series. Consecutive 58 patients (58 eyes) were randomly assigned to the one of the study groups regarding postoperative treatment. Patients in Group I used 0.09% bromfenac 2 times diurnally for 30 days, and patients in Group II used 0.5% loteprednol etabonate 4 times diurnally for 30 days. The laser flare-cell photometry, slit lamp examination, tonometry and optical coherence tomography of macula were performed preoperatively and postoperatively at 1, 7, 30 and 90 days. Results: The distance best corrected visual acuity was 0. 93 in group I and 0.91 in w group II. Laser Flare Photometry, central macular thickness and intraocular pressure was not significantly different during the 3 months of treatment between the groups (p> 0.05). In both groups, there were no abnormalities in routine slit lamp examination of the anterior and posterior segment. Conclusions: The results of the study suggest that topical bromfenac and topical loteprednol etabonate had similar effect on laser flare-cell photometry and foveal thickness in the postoperative period after uneventful phacoemulsification.