Comparison of efficacy and safety of different minimally invasive therapies for thyroid nodules: A network meta-analysis

Multidisciplinary Management of Advanced Thyroid Cancer

“…Radiation therapy, radiofrequency ablation, and ethanol ablation can be used for patients who do not wish to pursue systemic treatment and who have relatively indolent disease. 4,5 The slow growth rate of many differentiated thyroid carcinomas makes clinical trials difficult because of the time required to assess for response. Basket trials, which assign patients to specific drugs on the basis of molecular alterations, provide a promising approach to identifying patients most likely to benefit from a specific drug, but lack clear data for a specific subtype of cancer such as differentiated thyroid cancers.…”