Comparison of efficacy of narrow band UVB therapies with UVB alone, in combination with calcipotriol, and with betamethasoneand calcipotriol in vitiligo

Abstract

In conclusion, NB-UVB-alone therapy and the combined therapies are effective treatment options in the treatment of vitiligo. Future studies with larger groups are warranted to confirm our results.

Vitiligo Area Scoring Index and Vitiligo European Task Force assessment: reliable and responsive instruments to measure the degree of depigmentation in vitiligo

“…The hypotheses were as follows: (i) Repigmentation percentages of VASI and VETFa after 6 months will be ≥ 15% . (ii) There will be an intraclass correlation coefficient (ICC) ≥ 0·6 between the repigmentation percentages of VASI and VETFa and the percentages of improvement assessed by the treating physician.…”

“…11 The hypotheses were as follows: (i) Repigmentation percentages of VASI and VETFa after 6 months will be ≥ 15%. [12][13][14][15][16][17] (ii) There will be an intraclass correlation coefficient (ICC) ≥ 0Á6 between the repigmentation percentages of VASI and VETFa and the percentages of improvement assessed by the treating physician. (iii) Lesions in the face will have ≥ 10% higher repigmentation than lesions on the hands, as determined by VASI; and ≥ 10% higher than lesions on the hands and arms as determined by VETFa.…”

A comparative study of combined treatment with fractional carbon dioxide and targeted ultraviolet B phototherapy for facial vitiligo

“…Despite many existing treatment modalities, the response is largely variable, sometimes requiring prolong and robust treatment course [1]. The combination treatment with phototherapy and topical medications often shows superior degree of improvement compared to topical treatment monotherapy [5][6][7].…”

Combined therapy for resistant vitiligo lesions: NB-UVB, microneedling, and topical latanoprost, showed no enhanced efficacy compared to topical latanoprost and NB-UVB

“…The combination of the above treatment modalities was selected due to several reasons: Although data on prostaglandin use in vitiligo treatment are modest, therapeutic results are encouraging , and latanoprost combined with NB‐UVB is superior over either one ; Needling is used for treating localized vitiligo alone or in combination with NB‐UVB with quite satisfying therapeutic results . Up to now, nobody investigated microneedling with Dermaroller ® , an improved device for needling with controlled needle penetration depth, as a vitiligo therapeutic modality ; NB‐UVB is considered as a “golden standard” in vitiligo treatment with high repigmentation rate, which is further increased when combined with other therapeutic options . …”

“…Up to now, nobody investigated microneedling with Dermaroller V R , an improved device for needling with controlled needle penetration depth, as a vitiligo therapeutic modality (6,7); 3. NB-UVB is considered as a "golden standard" in vitiligo treatment with high repigmentation rate, which is further increased when combined with other therapeutic options (1,8).…”