Comparison of Efficacy of Treatment with Oral Ferrous Sulfate or Intravenous Iron Sucrose in the Treatment of Mild to Moderate Iron Deficiency Anemia in Pregnancy

Eralil, Georgy Joy

doi:10.5005/jp-journals-10028-1295

Cited by 1 publication

(2 citation statements)

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“…19 Eralil et al study shows mean age in years for oral iron group as 26.58±4.24 and in intravenous iron group as 26.09±4.47 with a p value of 0.59. 20 In the present study the peripheral smear of 76% women was found with microcytic anaemia and 24% others in both the groups. Similar results were seen in the study by Qurram et al in which peripheral smear of oral iron therapy group was 70% with microcytic anaemia and 30% with others and in intravenous iron therapy group 72% for microcytic and 28% for others with a chi square value of 0.096 which was statistically insignificant.…”

Section: Resultssupporting

confidence: 51%

“…18 According to Eralil et al study the serum haemoglobin increase in oral iron group was 1.09 and for intravenous iron group was 1.49 with a p value of 0.105 which was statistically insignificant. 20 According to Tigga et al the haemoglobin increase was found in oral iron group was 2.9 and for intravenous iron group 4.03 with a p value of 0.01 which was statistically significant. 22 In the present study the difference in mean serum ferritin in oral iron therapy as well as intravenous group was found increased at 3 rd weeks and at 8 th weeks from the baseline as p value was found <0.0001.…”

Section: Resultsmentioning

confidence: 89%

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Oral versus intravenous iron therapy among pregnant women with iron deficiency anaemia: a comparative study

Tonge

Dasila

Pote

2023

Int J Reprod Contracept Obstet Gynecol

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Background: Anaemia during pregnancy is considered to be a serious health concern. Whilst oral supplementation is most prevalent, it is also possible to provide iron parentally to replace the deficit. Methods: An observational study was conducted in the department of obstetrics and gynaecology of a tertiary care hospital, in Maharashtra. Total 110 women with iron deficiency anaemia were randomly divided into two groups using computer generated random numbers. Group A received oral iron therapy and group B received intravenous sucrose therapy. The haemoglobin and serum ferritin were assessed before and after treatment. Results: In the oral iron therapy group the age ranged between 19.3 to 27.1 years and in intravenous iron therapy group from 19.2 and 26.5 years. Baseline (0 day) haemoglobin in oral iron therapy group was 8.21±1.12 gm/dl and 8.36±1.14 gm/dl in intravenous iron group. The mean difference of 3.38 gm/dl was seen in the intravenous therapy group at 8th weeks against the mean difference of 1.63 gm/dl in oral iron therapy group. The mean difference of serum ferritin 18.92 µg/l was found in the oral iron therapy at the 8th week while the mean difference of 63.79 µg/l was seen in the intravenous therapy group. Conclusions: The intravenous sucrose therapy is found to be safe and effective alternative treatment for iron deficiency anaemia in pregnancy though the cost of treatment is significantly higher than the oral therapy.

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Section: Resultssupporting

confidence: 51%

Section: Resultsmentioning

confidence: 89%