Comparison of efficacy of two different silicone hydrogel bandage contact lenses after T-PRK

Abstract

AIM: To compare the efficacy between two different silicone hydrogel bandage contact lenses after transepithelial photorefractive keratectomy (T-PRK). METHODS: In this randomized controlled trial, a total of 89 patients (178 eyes) who underwent T-PRK at the Qingdao Eye Hospital from October to December 2019 were selected. One random eye wore a Senofilcon A bandage contact lens after surgery, and the other eye a Balafilcon A bandage contact lens. Pain scores, uncorrected visual acuity (UCVA), spherical equivalent (SE), corneal epithelial healing status, epithelial thickness, bandage lenses deposits, lenses movement, and ocular surface conditions were measured and compared. RESULTS: There were no differences between the two groups in UCVA, SE, corneal epithelial healing status, corneal epithelial thickness, tear river heights and tear film rupture time at each follow-up visit. However, postoperative pain scores in the Senofilcon A group were significantly lower than those of the Balafilcon A group (Fintergroups=67.833, P<0.001; Ftime=383.773, P<0.001; Finteraction=57.344, P<0.001). The duration of pain in eyes in the Senofilcon A group was shorter than that of the Balafilcon A group (t=-3.326, P=0.001). The surface deposition scores and movement scores of Senofilcon A bandage lenses on the first and fourth days after surgery were lower than those of Balafilcon A bandage lenses (Z=-5.385, -6.782, P<0.001; Z=-8.336, -8.906, P<0.001). CONCLUSION: Both Senofilcon A and Balafilcon A bandage lenses have good efficacy after T-PRK. Senofilcon A lenses are associated with less pain and more comfort compared to Balafilcon A.

Effects of Lotrafilcon A and Senofilcon A Bandage Contact Lenses on Visual Outcome and Ocular Comfort after Photorefractive Keratectomy (Effects of Two Different Bandage Contact Lens Following PRK)

“…However, Senofilcon A bandage contact lenses were associated with less pain in the first few days after surgery and were more comfortable to use after Transepithelial-PRK (T-PRK). They speculated that the edge design of BCLs and the mobility of the lens on the de-epithelized cornea may play a role in early postoperative pain outcomes [36]. A possible reason for the lack of visual rehabilitation difference observed between their study and the present study could be that they preferred T-PRK instead of alcohol-assisted epithelial debridement, which may have influenced the outcomes.…”

Clinical alteration with nearly application of silicone hydrogel contact lenses after small incision lenticule extraction

“…Silicone hydrogel lenses possess an oxygen permeability 5 to 6 times as high as that of hydrogel lenses [12] and are suitable for continuous wearing with better comfort. Appllications of silicone hydrogel lenses as bandage lenses have been reported effective after LASEK and T-PRK associated with less pain and more comfort [3,13]. However, there are also studies suggestting that patients felt less discomfort in eyes treated with a BCL after FS-LASIK than in control eyes and the tting of a silicone-hydrogel BCL after uneventful LASIK provoked morphological changes in theocular structures that may lead to a worse UCVA outcome [14,15].…”