Cardiac syndrome X (CSX) is a clinical condition, characterized by angina, positive stress test and negative coronary angiography. Myocardial ischemia is suggested to influence the ischemic changes in the electrocardiogram (ECG), observed during stress test. The aim of this study, is to obtain CSX patterns of the high-resolution vectorcardiographic (VCG) loops in the horizontal (H), frontal (F) and right sagittal (RS) planes of the Frank corrected orthogonal leads (X,Y, Z), and to assess their similarity with the reference VCG loops of normal subjects. The results suggest that CSX VCG profile in resting state could be considered as a variant of the normal profile; however, it contains some VCG changes seen in the ischemic heart disease.