Comparison of Endoscopic Ultrasonography and Conventional Endoscopy for Prediction of Tumor Depth in Superficial Nonampullary Duodenal Epithelial Tumors

Matsuda, Nobuyuki; Hirose, Takashi; Kakushima, Naomi; Furune, Satoshi; Ishikawa, Eri; Sawada, Tsunaki; Maeda, Keisuke; Yamamura, Takeshi; Ishikawa, Takuya; Ohno, Eizaburo; Nakamura, Masanao; Honda, Takashi; Ishigami, Masatoshi; Kawashima, Hiroki; Fujishiro, Mitsuhiro

doi:10.1159/000524841

Cited by 3 publications

(1 citation statement)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Routine preoperative work-up, including upper gastrointestinal endoscopy with biopsy, CT scans of the chest/abdomen/pelvis, and magnetic resonance imaging of the liver were routinely obtained [3]. We did not perform routine preoperative endoscopic ultrasonography (EUS) in this cohort because of the difficulty in predicting tumor depth for DA by EUS [10]. The regional lymphadenectomy in PSDD was classified into two groups: without (Level I dissection) or with (Level II dissection) mesopancreas dissection.…”

Section: Methodsmentioning

confidence: 99%

Treatment Strategy of Pancreas‐Sparing Distal Duodenectomy for Distal Duodenal Malignancies with Adjustable Dissection Levels According to Disease Progression (with Video)

Kato

Oba

et al. 2023

World j. surg.

View full text Add to dashboard Cite

Background Pancreas‐sparing distal duodenectomy (PSDD) is a favorable option for distal duodenal neoplasms, and its procedure, including the extent of lymphadenectomy, should be modified according to the malignancy of the tumor. However, there are no coherent reports on the details of this procedure or long‐term outcomes after each resection. Methods This study included 24 patients who underwent PSDD at our institution between January 2009 and October 2020. Patients were divided into two groups according to the tumor progression: nine with (Lv‐II) and fifteen without (Lv‐I) mesopancreas dissection. Postoperative outcomes were compared between the two groups. Results Two groups had similar operation times, blood loss, hospital stay, and the rate of delayed gastric emptying (DGE): 40% versus 44%. There were no Clavien–Dindo classification ≥ III complications in the Lv‐II group. The Lv‐II group had a larger number of examined lymph nodes (median: 29), and three (33%) patients had lymph node metastasis. No local recurrence was observed, although two patients in the Lv‐II group had liver metastasis. The 5‐year overall survival rates of the Lv‐I and Lv‐II groups were 100% and 78%, respectively. None of the patients had an impaired nutrition status after one year of surgery, and no rehospitalization was observed in either group. Conclusion Although PSDD with or without mesopancreas dissection entailed a high risk of DGE, this procedure showed favorable long‐term outcomes and may be an alternative to pancreatoduodenectomy in patients with distal duodenal neoplasms.

show abstract

Section: Methodsmentioning

confidence: 99%

Treatment Strategy of Pancreas‐Sparing Distal Duodenectomy for Distal Duodenal Malignancies with Adjustable Dissection Levels According to Disease Progression (with Video)

Kato

Oba

et al. 2023

World j. surg.

View full text Add to dashboard Cite

show abstract

Esophagogastroscopy for predicting endoscopic ultrasonography T-stage by utilizing deep learning methods in esophageal cancer

Zhang,

Chen,

Wang

et al. 2024

Appl Intell

View full text Add to dashboard Cite

Endoscopic ultrasonography (EUS) is commonly utilized in preoperative staging of esophageal cancer, however with additional pain and cost as well as adverse events. Meanwhile, the accuracy of EUS is highly depend on the training and practice of operators and not universally available. Different operators would lead to high inter-observer variability. Therefore, it is desirable to explore an alternative way to determine preoperative T stage in esophageal cancer. Whether conventional endoscopy possess the ability to predict EUS T stage has never been investigated yet. In current study, with the assistance of Artificial intelligence, we have developed a deep learning model to predict EUS T stage based on 9,714 images collected from 3,333 patients. ResNet-152 pre-trained on the ImageNet dataset was trained with the appropriate transfer learning and fine-tuning strategies on the conventional endoscopic images and their corresponding labels (e.g., T1, T2, T3, T4 and Normal). Meanwhile, augmentation strategies including rotation and flipping were performed to increase the number of images to improve the prediction accuracy. Finally, 4,382 T1, 243 T2, 3,985 T3, 1,102 T4, 14,302 controls images were obtained and split into training dataset, validation dataset and independent testing dataset with the ratio of 4:1:1. Our model could achieve a satisfied performance with an area under the receiver-operating curve (AUC) were 0.9767, 0.9637, 0.9597 and 0.9442 for T1, T2, T3 and T4, respectively in independent testing dataset. In conclusion, conventional gastroscopy combined with artificial intelligence have the great potential to predict EUS T stage.

show abstract

Superficial non-ampullary duodenal epithelial tumors now: endoscopic diagnosis and therapy

Hirose

Kato

Hatta

et al. 2023

Japanese Journal of Clinical Oncology

View full text Add to dashboard Cite

With the recent increase in the frequency of duodenal tumor detection, significant progress has been made in endoscopic diagnosis and treatment. Although the first guidelines were issued in Japan, patient treatment varies widely among institutions. There is a need for improving the quality of endoscopic diagnosis and more curative and safer treatments. Biopsy is the standard diagnostic method; however, the diagnostic accuracy of endoscopic biopsy is not so high. Therefore, the differentiation of superficial non-ampullary duodenal epithelial tumors from non-neoplastic lesions is being developed. The incidence of lymph node and distant metastases of duodenal epithelial tumors is extremely rare in intramucosal carcinomas, and they are considered good candidates for endoscopic treatment if the technical difficulties can be resolved. Adverse events associated with endoscopic treatment are greatly reduced at advanced facilities through novel resection and closure methods, and further improvements are expected in the future. Clarifying the risk of metastatic recurrence may lead to the development of more appropriate treatments and curative resection criteria.

show abstract

Comparison of Endoscopic Ultrasonography and Conventional Endoscopy for Prediction of Tumor Depth in Superficial Nonampullary Duodenal Epithelial Tumors

Cited by 3 publications

References 26 publications

Treatment Strategy of Pancreas‐Sparing Distal Duodenectomy for Distal Duodenal Malignancies with Adjustable Dissection Levels According to Disease Progression (with Video)

Treatment Strategy of Pancreas‐Sparing Distal Duodenectomy for Distal Duodenal Malignancies with Adjustable Dissection Levels According to Disease Progression (with Video)

Esophagogastroscopy for predicting endoscopic ultrasonography T-stage by utilizing deep learning methods in esophageal cancer

Superficial non-ampullary duodenal epithelial tumors now: endoscopic diagnosis and therapy

Contact Info

Product

Resources

About