The integration of electrodialysis with bipolar membranes (EDBM) with seawater reverse osmosis (SWRO) process influences the two main environmental burdens of SWRO desalination process: climate change, associated to the high-energy consumption, and the environmental alteration of the vicinities of the facility, due to brine disposal. EDBM powered by photovoltaic (PV) solar energy is able to meet the abovementioned challenges that arise in SWRO desalination. In addition, HCl and NaOH, both employed in desalination industry, can be produced from the brines. Hence, environmental benefits regarding the potential self-supply can be achieved. The environmental sustainability assessment by means of Life Cycle Assessment (LCA) of a SWRO and EDBM has been carried out considering four different scenarios. The percentage of treated brines and the influence of the grid mix used for electric power supply has been taken into account. The three different electric power supplies were: 100.0% renewable energy (PV solar energy), 36.0% renewable energy