Comparison of EOSQ-24 and SRS-22 Scores in Congenital Scoliosis: A Preliminary Study

Abstract

Background: The 24-item Early-Onset Scoliosis Questionnaire (EOSQ-24) and 22-item Scoliosis Research Society (SRS-22) questionnaire measure health-related quality of life in patients with scoliosis. The EOSQ-24 has been recently validated in early-onset scoliosis (EOS), including congenital scoliosis (CS). The SRS-22 has been validated in idiopathic scoliosis. The EOSQ-24 is completed by the caregiver and the SRS-22 is completed by the patient. The primary purpose of this study was to compare the EOSQ-24 and SRS-22 in patients with CS. The secondary purpose was to compare scores by age and also in developmentally delayed patients. We hypothesized that the SRS-22 is appropriate for children with EOS from CS who do not have a diagnosis of developmental delay. Methods: This was a prospective comparative study. A prospective institutional CS database was queried to identify patients who had the EOSQ-24 and SRS-22 completed at the same time point. Children without a diagnosis of developmental delay completed both questionnaires if they understood the questions, regardless of age. Otherwise, the caregiver completed both questionnaires. For the analysis, similar questions were matched so that the EOSQ-24 questions fit into the SRS-22 domains of Function, Pain, Mental Health, and Satisfaction. Pearson correlation coefficients (r) were used to compare domain scores, with r≥0.70 indicating a strong relationship. Results: The final study group included 98 patients. The average age at completion of the questionnaires was 9.5 years. A strong correlation was found for all domains except Satisfaction when the patient or caregiver completed both questionnaires. Subanalysis demonstrated the strongest relationship between domains in the age group 0 to 5 years. In developmentally delayed patients, a weak correlation was noted for all domain scores except Pain, which showed a strong correlation. There was a strong correlation for Pain and a weak correlation for Satisfaction domains across all subgroups. Conclusions: The SRS-22 may be appropriate for children with EOS from CS who do not have a diagnosis of developmental delay. Our findings suggest that the results of previous studies that collected the SRS-22 and future studies that collect the EOSQ-24 can be correlated. It remains unclear which questionnaire is more suitable for developmentally delayed patients. Level of Evidence: Level I—diagnostic.

Outcomes of early hemivertebrectomy in children with congenital scoliosis: A prospective follow-up study

“…The difficulties encountered in this evaluation include their young age, and therefore, we asked their parents to fulfill these questionnaires. 22 In accordance with our hypothesis, the long immobilization (cast 6 weeks and brace 3 months) decreased their QoL at 6 months, although the function domain of the SRS-24 improved further to final follow-up. Future research needs to address ways to decrease the incidence of skin-related complications.…”

“…The SRS-24 questionnaire has not been used previously in this patient group, but SRS-22, the modification of this original questionnaire, has recently shown a good correlation with the EOSQ-24 questionnaire in this patient population. 22…”

“…In addition, the SRS-22 questionnaire, which is a modification of the original SRS-24, has been shown to provide similar results as the early onset scoliosis questionnaire 24 (EOSQ-24) in congenital scoliosis with the strongest relationship between the age group between 0 and 5 years. 22 The domains of the SRS questionnaire used in this questionnaire such daily activities outside the home may reflect more the QoL in teenagers and not in smaller children. The HRQoL assessment did not take into account the normal development during childhood, for example, starting to walk around the age of one.…”

Cross-Cultural Adaptation and Validation of the Persian Version of the 24-Item Early-Onset Scoliosis Questionnaire

“…The original version of the SRS-22 was developed for adolescents who had idiopathic scoliosis [ 23 ]. However, recently, Li et al [ 28 ] conducted a study on patients with congenital scoliosis and found that except for the satisfaction domain, there was a strong correlation between all the sub-domains of the SRS-22 and EOSQ-24. Therefore, SRS-22 is a good instrument for investigating the convergent validity of the EOSQ-24.…”

Disease-Specific Outcome Measures Evaluating the Health-Related Quality of Life of Children and Adolescents with Idiopathic Scoliosis and Scheuermann's Kyphosis: A Literature Review

“…Although the SRS-22 has also been used to assess the HRQoL of patients with congenital scoliosis 92) , this questionnaire has several limitations and poorly reflects other important aspects of a patient's life. In EOS, factors such as pulmonary function, fatigue, and parental burden are arguably more essential factors to evaluate than for other types of adolescent or adult scoliosis.…”