Comparison of epidemiological characteristics and transmissibility of different strains of COVID-19 based on the incidence data of all local outbreaks in China as of March 1, 2022

Yan, Ning; Luo, Lei; Yang, Shiting; Abudurusuli, Guzainuer; Zhao, Zeyu; Rui, Jia; Li, Zhuoyang; Deng, Bin; Liu, Weikang; Zhang, Zhe; Li, Kangguo; Liu, Chan; Li, Peihua; Huang, Jiefeng; Yang, Tianlong; Wang, Yao; Chen, Tianmu; Li, Qun

doi:10.3389/fpubh.2022.949594

Cited by 6 publications

(2 citation statements)

References 55 publications

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“…7 However, this high vaccine coverage did not prevent the unprecedented transmission and epidemic growth of the Omicron variant in late 2021 and early 2022. 8,9 Given the immune evasion and high transmissibility of the Omicron variant, 10 most people in Canada now have infection-acquired immunity and vaccineinduced immunity, ushering in an era of hybrid immunity. 11,12 The low infection rate in Canada before the arrival of the Omicron variant was observed in other high-income countries in North America and Europe.…”

Section: Discussionmentioning

confidence: 99%

The evolution of SARS-CoV-2 seroprevalence in Canada: a time-series study, 2020–2023

Murphy,

Swail,

Jain

et al. 2023

CMAJ

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Background: During the first year of the COVID-19 pandemic, the proportion of reported cases of COVID-19 among Canadians was under 6%. Although high vaccine coverage was achieved in Canada by fall 2021, the Omicron variant caused unprecedented numbers of infections, overwhelming testing capacity and making it difficult to quantify the trajectory of population immunity. Methods: Using a time-series approach and data from more than 900 000 samples collected by 7 research studies collaborating with the COVID-19 Immunity Task Force (CITF), we estimated trends in SARS-CoV-2 seroprevalence owing to infection and vaccination for the Canadian population over 3 intervals: prevaccination (March to November 2020), vaccine roll-out (December 2020 to November 2021), and the arrival of the Omicron variant (December 2021 to March 2023). We also estimated seroprevalence by geographical region and age. Results: By November 2021, 9.0% (95% credible interval [CrI] 7.3%–11%) of people in Canada had humoral immunity to SARS-CoV-2 from an infection. Seroprevalence increased rapidly after the arrival of the Omicron variant — by Mar. 15, 2023, 76% (95% CrI 74%–79%) of the population had detectable antibodies from infections. The rapid rise in infection-induced antibodies occurred across Canada and was most pronounced in younger age groups and in the Western provinces: Manitoba, Saskatchewan, Alberta and British Columbia. Interpretation: Data up to March 2023 indicate that most people in Canada had acquired antibodies against SARS-CoV-2 through natural infection and vaccination. However, given variations in population seropositivity by age and geography, the potential for waning antibody levels, and new variants that may escape immunity, public health policy and clinical decisions should be tailored to local patterns of population immunity.

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Section: Discussionmentioning

confidence: 99%

The evolution of SARS-CoV-2 seroprevalence in Canada: a time-series study, 2020–2023

Murphy,

Swail,

Jain

et al. 2023

CMAJ

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“…During the Omicron dominance, there was an increase in the number of COVID-19 cases, primary infections, and reinfections in HCWs, although most of the HCWs were vaccinated with the primary schedule, and some also had the first booster administered. The assumption that the high number of infections could be explained by the increased transmissibility of Omicron variants has been demonstrated in multiple studies worldwide [ 15 , 16 , 32 ].…”

Section: Discussionmentioning

confidence: 99%

Hybrid Immunity and the Incidence of SARS-CoV-2 Reinfections during the Omicron Era in Frontline Healthcare Workers

Chivu,

Crăciun,

Pițigoi

et al. 2024

Vaccines

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During the coronavirus disease (COVID-19) pandemic healthcare workers (HCWs) acquired immunity by vaccination or exposure to multiple variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Our study is a comparative analysis between subgroups of HCWs constructed based on the number of SARS-CoV-2 infections, vaccination, and the dominant variant of SARS-CoV-2 in the population. We collected and analyzed data using the χ2 test and density incidence of reinfections in Microsoft Excel for Mac, Version 16.84, and MedCalc®, 22.026. Of the 829 HCWs, 70.1% (581) had only one SARS-CoV-2 infection and 29.9% (248) had two infections. Of the subjects with two infections, 77.4% (192) worked in high-risk departments and 93.2% (231) of the second infections were registered during Omicron dominance. The density incidence of reinfections was higher in HCWs vaccinated with the primary schedule than those vaccinated with the first booster, and the incidence ratio was 2.8 (95% CI: 1.2; 6.7). The probability of reinfection was five times lower (95% CI: 2.9; 9.2) in HCWs vaccinated with the primary schedule if the first infection was acquired during Omicron dominance. The subjects vaccinated with the first booster had a density incidence of reinfection three times lower (95% CI: 1.9; 5.8) if the first infection was during Omicron. The incidence ratio in subgroups constructed based on characteristics such as gender, age group, job category, and department also registered significant differences in density incidence. The history of SARS-CoV-2 infection by variant is important when interpreting and understanding public health data and the results of studies related to vaccine efficacy for hybrid immunity subgroup populations.

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Profil épidémiologique et clinique de la COVID-19 chez le personnel de santé de l’hôpital Aziza Othmana, Tunis, Tunisie

Salem¹,

Hannachi²,

Kalai³

et al. 2023

Archives des Maladies Professionnelles et de l'Environnement

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Comparison of epidemiological characteristics and transmissibility of different strains of COVID-19 based on the incidence data of all local outbreaks in China as of March 1, 2022

Abstract: Comparison of epidemiological characteristics and transmissibility of di erent strains of COVID-based on the incidence data of all local outbreaks in China as of March , .

Cited by 6 publications

References 55 publications

The evolution of SARS-CoV-2 seroprevalence in Canada: a time-series study, 2020–2023

The evolution of SARS-CoV-2 seroprevalence in Canada: a time-series study, 2020–2023

Hybrid Immunity and the Incidence of SARS-CoV-2 Reinfections during the Omicron Era in Frontline Healthcare Workers

Profil épidémiologique et clinique de la COVID-19 chez le personnel de santé de l’hôpital Aziza Othmana, Tunis, Tunisie

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