Comparison of Epidemiological Variations in COVID-19 Patients Inside and Outside of China—A Meta-Analysis

Ahmed, Aziza; Ali, Aman; Hasan, Sana

doi:10.3389/fpubh.2020.00193

Cited by 30 publications

(35 citation statements)

References 26 publications

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“…A few systematic review studies looking at COVID-19 risk factors, clinical characteristics and predictive models identified male sex as a risk factor for either disease incidence or mortality ( 25 , 51 , 68 – 70 ). Our study findings further confirm these observations.…”

Section: Discussionmentioning

confidence: 99%

Systematic Review and Meta-Analysis of Sex-Specific COVID-19 Clinical Outcomes

et al. 2020

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To successfully mitigate the extraordinary devastation caused by the Coronavirus disease 2019 (COVID-19) pandemic, it is crucial to identify important risk factors for this disease. One such neglected health determinant is the sex of the patient. This is an essential clinical characteristic, as it can factor into a patient's clinical management and preventative measures. Some clinical studies have shown disparities in the proportion between males and females that have more severe clinical outcomes or, subsequently, die from this disease. However, this association has not been unequivocally established. Thus, the purpose of this investigation was to examine the association between male sex and COVID-19 severity. We systematically reviewed the literature, identified studies that matched predetermined selection criteria, and performed a meta-analysis to evaluate the proportion of males among four disease severity categories. Appropriate assessment strategies were implemented to assess and minimize potential biases. The results of this meta-analysis indicated that males constituted a significantly higher proportion of those who had adverse clinical outcomes and died from COVID-19. As the coronavirus spread from the East to the West, male sex remained a consistent risk factor. Our results support the establishment of the male sex as an important risk factor for this disease. Early identification and appropriate medical care for males with lab-confirmed COVID-19 may substantially change the course of clinical prognosis, resulting in greater numbers of lives saved.

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Section: Discussionmentioning

confidence: 99%

Systematic Review and Meta-Analysis of Sex-Specific COVID-19 Clinical Outcomes

et al. 2020

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“…Median ages among Hispanic (71 years)and nonwhite decedents (72 years) was 9–10 years lower than that of white decedents (81 years) ( 8 , 12 ).As per an Indian news column, 43% deaths have taken place in the relatively younger age groups of 30-44 and 45-59 years(13). ( 4 )As per a Meta analysis, the median age range is 28–70 in the 13 selected studies. Average median age was 47 ± 7 years.…”

Section: Introductionmentioning

confidence: 99%

Morbidity and mortality trends of Covid 19 in top 10 countries

Matta

Chopra

Arora³

2020

Indian Journal of Tuberculosis

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The present article highlights morbidity and mortality trends of Covid 19 in the last 3 months in top 10 countries of the world. In spite of efforts being undertaken, all countries are showing an increasing trend in terms of morbidity and mortality.The order of countries in terms of mortality and morbidity has changed in the last 3 months.Various efforts are being undertaken by WHO and other agencies world over including the vaccine development initiative.

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“…The genome and genetic shift of such coronaviruses are shown in Figure 2. A similar type of outbreak occurred during the middle of January of 2003 until the last week of February of the same year, during the Spring Festival, or Lunar New Year, in China (Ali et al, 2020). This newest outbreak also peaked between the first and third weeks of January 2020 .…”

Section: Epidemiologymentioning

confidence: 79%

Recent Advances in Pathophysiology, Drug Development and Future Perspectives of SARS-CoV-2

Singh

Han

Choi

et al. 2020

Front. Cell Dev. Biol.

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The coronavirus (SARS-CoV-2) pandemic is a rapidly transmitting and highly pathogenic disease. The spike protein of SARS-CoV-2 binds to the surface of angiotensinconverting enzyme-2 (ACE2) receptors along the upper respiratory tract and intestinal epithelial cells. SARS-CoV-2 patients develop acute respiratory distress, lymphocytic myocarditis, disseminated intravascular coagulation, lymphocytic infiltration, and other serious complications. A SARS-CoV-2 diagnosis is conducted using quantitative reverse-transcription PCR and computed tomography (CT) imaging. In addition, IgM or IgG antibodies are used to identify acute and convalescent illness. Recent clinical data have been generated by health workers and researchers and have shown that there is an urgent requirement in the effective clinical and treatment of patients, as well as other developments for dealing with SARS-CoV-2 infection. A broad spectrum of clinical trials of different vaccines and drug treatment has been evaluated for use against SARS-CoV-2. This review includes the emergence of SARS-CoV-2 pneumonia as a way to recognize and eliminate any barriers that affect rapid patient care and public health management against the SARS-CoV-2 epidemic based on the natural history of the disease, its transmission, pathogenesis, immune response, epidemiology, diagnosis, clinical presentation, possible treatment, drug and vaccine development, prevention, and future perspective.

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Comparison of Epidemiological Variations in COVID-19 Patients Inside and Outside of China—A Meta-Analysis

Abstract: The objective of this study is to compare the epidemiological variations in COVID-19 patients reported in studies from inside and outside of China. We selected COVID-19 observational studies from eight countries, including,

Cited by 30 publications

References 26 publications

Systematic Review and Meta-Analysis of Sex-Specific COVID-19 Clinical Outcomes

Systematic Review and Meta-Analysis of Sex-Specific COVID-19 Clinical Outcomes

Morbidity and mortality trends of Covid 19 in top 10 countries

Recent Advances in Pathophysiology, Drug Development and Future Perspectives of SARS-CoV-2

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