Comparison of Equivalent Spherical Volume and Aerodynamic Diameters for Irregularly Shaped Particles

Tomb, T.F.; Corn, Morton

doi:10.1080/0002889738506801

Cited by 6 publications

(5 citation statements)

References 2 publications

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“…It was reported the aerodynamic diameter da of talc was smaller than the projected area diameter dp [46]. The Stokes diameter of mica was smaller than the equivalent volume diameter [62]. Our research and above studies showed that fiber-like shaped particles were not the only case possessing small aerodynamic diameter, the plate-like shaped particles also had small aerodynamic diameter compared to the geometric lateral size.…”

Section: Discussionsupporting

confidence: 44%

Quantifying respiratory tract deposition of airborne graphene nanoplatelets: The impact of plate-like shape and folded structure

et al. 2021

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Section: Discussionsupporting

confidence: 44%

Quantifying respiratory tract deposition of airborne graphene nanoplatelets: The impact of plate-like shape and folded structure

et al. 2021

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“…Usually only particles less than 5 /-lm are expected to reach the lung. Tomb & Corn (57) found that mica particles tested in a horizontal elutriator did not assume a preferred orientation during settling and that the orientation influenced the settling velocity. A reduction in the settling velocity would permit larger particles to be deposited at places where only smaller particles would be expected.…”

Section: Experimental Studiesmentioning

confidence: 99%

Mica pneumoconiosis--a literature review.

Skulberg¹,

Gylseth²,

Skaug³

et al. 1985

Scand J Work Environ Health

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This article in PubMed: www.ncbi.nlm.nih.gov/pubmed/3890162 Scand J Work Environ Health 11 (1985) 11 (1985) 65-74. Sixty-six cases of mica pneumoconiosis have been reported in the literature. Twenty-six of the cases suggest that pneumoconiosis may be caused by pure mica alone. In only six cases the diagnosis was based on clinical examination, radiography, and lung biopsy or autopsy results. In one of these six, doubt was raised by the authors about the purity of the mica exposure. Seven epidemiologic studieshave been performed among mica-processing workers, and these studies are all cross-sectional. In addition 30 experimental investigations have been carried out. However, there are no controlled inhalation studies among them. The results from the intratracheal instillation studies do not give a unanimous conclusion as to whether pure mica is fibrogenic or not. Present knowledge suggests that pure mica is moderately toxic and may induce pneumoconiosis. Exposure to mica is usually associated with exposure to other minerals such as quartz and feldspar. REVIEWS

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“…It was reported the aerodynamic diameter d a of talc was smaller than the projected area diameter d p [43]. The Stokes diameter of mica was smaller than the equivalent volume diameter [44]. Our research and above studies showed that fiber-like shaped particles were not the only case possessing small aerodynamic diameter, the plate-like shaped particles also had small aerodynamic diameter compared to the geometric lateral size.…”

Section: Discussionmentioning

confidence: 47%

Quantifying respiratory tract deposition of airborne graphene nanoplatelets: The impact of plate-like shape and folded structure

Gao

Hammer

Zhang

et al. 2020

Preprint

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The booming development of commercial products containing graphene nanoplatelets (GNPs) triggers growing concerns over their release into the air. Precise prediction of human respiratory system deposition of airborne GNPs, especially in alveolar region, is very important for inhalation exposure assessment. In this study, the pulmonary deposition of airborne GNPs was predicted by the multiple-path particle dosimetry (MPPD) model with consideration of GNPs plate-like shape and folded structure effect. Different equivalent diameters of GNPs were derived and utilized to describe different deposition mechanisms in the MPPD model. Both of small GNPs (geometric lateral size dg < 0.1 μm) and large GNPs (dg > 10 μm) had high deposition fractions in human respiratory system. The total deposition fractions for 0.1 μm and 30 μm GNPs were 41.6% and 75.6%, respectively. Most of the small GNPs deposited in the alveolar region, while the large GNPs deposited in the head airways. The aerodynamic diameter of GNPs was much smaller than the geometric lateral dimension due to the nanoscale thickness. For GNPs with geometric lateral size of 30 μm, the aerodynamic diameter was 2.98 μm. The small aerodynamic diameter of plate-like GNPs enabled deposition in the alveolar region, and folded GNPs had higher alveolar deposition than planar GNPs. Heavy breathing led to higher GNPs deposition fraction in head airways and lower deposition fractions in the alveolar region than resting breathing. Our results reveal that large GNPs can have small enough aerodynamic diameters to be respirable and deposit beyond the ciliated airways. The plate-like morphology and folded structure of GNPs resulted in higher alveolar deposition compared to spherical particles.

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Comparison of Equivalent Spherical Volume and Aerodynamic Diameters for Irregularly Shaped Particles

Cited by 6 publications

References 2 publications

Quantifying respiratory tract deposition of airborne graphene nanoplatelets: The impact of plate-like shape and folded structure

Quantifying respiratory tract deposition of airborne graphene nanoplatelets: The impact of plate-like shape and folded structure

Mica pneumoconiosis--a literature review.

Quantifying respiratory tract deposition of airborne graphene nanoplatelets: The impact of plate-like shape and folded structure

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