Comparison of Esophageal Motility in Patients with Solid Dysphagia and Mixed Dysphagia

Abstract

It is unclear whether there is any difference in esophageal motor abnormalities between patients complaining of dysphagia for solids or both solids and liquids. The aim of this study was to determine any difference in the manometric findings between patients with dysphagia for solids and those with mixed dysphagia. Manometric tracings were performed in 200 consecutive patients (66 M, 134 F; mean age = 51 years) with nonobstructive dysphagia. Ambulatory pH studies were performed in all patients. Subjects were divided into two groups: patients with solid dysphagia (n = 94, 33 M, 61 F; mean age = 51 years) and those with mixed dysphagia (n = 106, 33 M, 73 F; mean age = 51 years). A normal motility study was the most frequent finding. Achalasia occurred more frequently in patients with mixed dysphagia than in those with solid dysphagia (12% vs. 3%, p < 0.01). Gastroesophageal reflux disease (GERD) was observed in 59% of patients with solid dysphagia compared with 29% of patients with mixed dysphagia (p < 0.02). The most common esophageal motility abnormality is nonspecific esophageal motility disorders. This study has shown that abnormal esophageal motility occurs slightly more in mixed dysphagia than solid dysphagia. The clinical utility of a symptomatic differentiation of patients with solid or mixed dysphagia appears to be limited.

Epidemiology of the Complications of Gastroesophageal Reflux Disease

“…They found that GERD was a risk factor for dysphagia as well as odynophagia; indeed, intermittent dysphagia and odynophagia were independently associated with GERD symptoms (OR: 2.96, 95% CI: 1.76-4.98; OR: 3.41, 95% CI: 1.16-10.04, respectively), but dysphagia was also associated with depression and anxiety. However, esophageal motility studies have shown that patients with solid dysphagia are more likely to have GERD than those with mixed dysphagia [21] .…”

Discussion of Prevalence and Management of Discomfort When Swallowing Pills: Orodispersible Tablets Expand Treatment Options in Patients With Depression

“…Furthermore, stroke and cancer of the head and neck may also result in dysphagia in response to morphologic changes or treatment effects [7]. Other physical disorders linked to dysphagia include hypertension and gastroesophageal reflux disease, which can cause scarring of the esophagus [8][9][10].…”

VIDEOFLUOROSCOPIC SWALLOWING STUDY: esophageal alterations in patients with dysphagia

“…Patients presenting alterations of the esophageal phase should be investigated through more specific tests, such as endoscopy, esophageal manometry and esophageal pH metry, because the VFSS is a screening tool that can aid in selection of other tests and disclose diagnosis of esophageal disorders (1,2,11,16,18) . Importantly, the screening of the esophageal phase of swallowing through videofluoroscopy is of short duration and can be easily carried out.…”