Comparison of exercise capacity in COPD and other etiologies of chronic respiratory failure requiring non-invasive mechanical ventilation at home: retrospective analysis of 1-year follow-up

Saltürk, Cüneyt; Karakurt, Zühal; Takır, Hurıye Berk; Balcı, Merih Kalamanoğlu; Kargın, Feyza; Moçin, Özlem Yazıcıoğlu; Güngör, Gökay; Özmen, İpek; Oztas, Selahattin; Yalçınsoy, Murat; Evin, Ruya; Öztürk, Murat; Adıgüzel, Nalan

doi:10.2147/copd.s91950

Cited by 10 publications

(6 citation statements)

References 41 publications

(41 reference statements)

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“…Short-term rates of hospitalization were reduced by PAP, but the event rate was low and data were reported in only one RCT ( 19 ). Longer-term data suggest high rates of hospitalization in patients with OHS on PAP but without a comparison group (data from five observational studies: 10% at 3 mo to 49% at 5 yr) ( 20 , 22 , 65 , 70 , 74 ).…”

Section: Resultsmentioning

confidence: 99%

Evaluation and Management of Obesity Hypoventilation Syndrome. An Official American Thoracic Society Clinical Practice Guideline

Mokhlesi¹,

Masa²,

Brožek³

et al. 2019

Am J Respir Crit Care Med

196

146

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; on behalf of the American Thoracic Society Assembly on Sleep and Respiratory Neurobiology THIS OFFICIAL CLINICAL PRACTICE GUIDELINE OF THE AMERICAN THORACIC SOCIETY WAS APPROVED MAY 2019 Background: The purpose of this guideline is to optimize evaluation and management of patients with obesity hypoventilation syndrome (OHS). Methods: A multidisciplinary panel identified and prioritized five clinical questions. The panel performed systematic reviews of available studies (up to July 2018) and followed the Grading of Recommendations, Assessment, Development, and Evaluation evidence-to-decision framework to develop recommendations. All panel members discussed and approved the recommendations. Recommendations: After considering the overall very low quality of the evidence, the panel made five conditional recommendations. We suggest that: 1) clinicians use a serum bicarbonate level ,27 mmol/L to exclude the diagnosis of OHS in obese patients with sleepdisordered breathing when suspicion for OHS is not very high (,20%) but to measure arterial blood gases in patients strongly suspected of having OHS, 2) stable ambulatory patients with OHS receive positive airway pressure (PAP), 3) continuous positive airway pressure (CPAP) rather than noninvasive ventilation be offered as the first-line treatment to stable ambulatory patients with OHS and coexistent severe obstructive sleep apnea, 4) patients hospitalized with respiratory failure and suspected of having OHS be discharged with noninvasive ventilation until they undergo outpatient diagnostic procedures and PAP titration in the sleep laboratory (ideally within 2-3 mo), and 5) patients with OHS use weight-loss interventions that produce sustained weight loss of 25% to 30% of body weight to achieve resolution of OHS (which is more likely to be obtained with bariatric surgery). Conclusions: Clinicians may use these recommendations, on the basis of the best available evidence, to guide management and improve outcomes among patients with OHS.

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Section: Resultsmentioning

confidence: 99%

Evaluation and Management of Obesity Hypoventilation Syndrome. An Official American Thoracic Society Clinical Practice Guideline

Mokhlesi¹,

Masa²,

Brožek³

et al. 2019

Am J Respir Crit Care Med

196

146

View full text Add to dashboard Cite

show abstract

“…The combination of home NIV and exercise training has been demonstrated to deliver a larger improvement in blood gases than either intervention alone (63). Home NIV resulted in a greater improvement in 6MWD when coupled with pulmonary rehabilitation than rehabilitation alone both in controlled and uncontrolled studies (64)(65)(66). However, systematic reviews and meta-analyses are unable to recommend the addition of NIV during exercise therapy due to the lack of supporting evidence (67)(68)(69).…”

Section: Niv As An Adjunct In Exercise Trainingmentioning

confidence: 99%

Update: non-invasive ventilation in chronic obstructive pulmonary disease

Shah¹,

D’Cruz²,

Murphy³

2018

J. Thorac. Dis.

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Chronic obstructive pulmonary disease (COPD) remains a common cause of morbidity and mortality worldwide. Patients with COPD and respiratory failure, whether acute or chronic have a poorer prognosis than patients without respiratory failure. Non-invasive ventilation (NIV) has been shown to be a useful tool in both the acute hospital and chronic home care setting. NIV has been well established as the gold standard therapy for acute decompensated respiratory failure complicating an acute exacerbation of COPD with reduced mortality and intubation rates compared to standard therapy. However, NIV has been increasingly used in other clinical situations such as for weaning from invasive ventilation and to palliate symptoms in patients not suitable for invasive ventilation. The equivocal evidence for the use of NIV in chronic hypercapnic respiratory failure complicating COPD has recently been challenged with data now supporting a role for therapy in selected subgroups of patients. Finally the review will discuss the emerging role of high flow humidified therapy to support or replace NIV in certain clinical situation.

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“…However, we know that there are studies demonstrating an enhanced exercise capacity with long-term NIV therapy in COPD patients [7,8]. We think that the 6-min walk test, which indicates a patient's exercise capacity, needs to be performed in addition to the SRI questionnaire while evaluating beneficial effects of NIV.…”

Section: Financial Disclosure and Conflicts Of Interestmentioning

confidence: 99%

COPD Patients Requiring Long-Term NIV Therapy: What Are the Critical Points in Monitoring the Efficacy of NIV?

Tunçay

Esquinas

2018

Respiration

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Comparison of exercise capacity in COPD and other etiologies of chronic respiratory failure requiring non-invasive mechanical ventilation at home: retrospective analysis of 1-year follow-up

Cited by 10 publications

References 41 publications

Evaluation and Management of Obesity Hypoventilation Syndrome. An Official American Thoracic Society Clinical Practice Guideline

Evaluation and Management of Obesity Hypoventilation Syndrome. An Official American Thoracic Society Clinical Practice Guideline

Update: non-invasive ventilation in chronic obstructive pulmonary disease

COPD Patients Requiring Long-Term NIV Therapy: What Are the Critical Points in Monitoring the Efficacy of NIV?

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