1999
DOI: 10.1016/s0149-2918(00)88287-9
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Comparison of extended-release venlafaxine, selective serotonin reuptake inhibitors, and tricyclic antidepressants in the treatment of depression: A meta-analysis of randomized controlled trials

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Cited by 91 publications
(48 citation statements)
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“…Another 2 meta-analyses were excluded because they overlapped with other meta-analyses [13,14]. In 6 of the 15 finally selected meta-analyses, outcome was defined as the proportion of responders [15,16,17,18,19,20], in 4 as proportion of remitters [21,22,23,24] and in 4 as both [25,26,27,28]. Only 1 meta-analysis [29] (on psychotherapy) defined outcome as effect size on the BDI [30].…”
Section: Methodsmentioning
confidence: 99%
See 1 more Smart Citation
“…Another 2 meta-analyses were excluded because they overlapped with other meta-analyses [13,14]. In 6 of the 15 finally selected meta-analyses, outcome was defined as the proportion of responders [15,16,17,18,19,20], in 4 as proportion of remitters [21,22,23,24] and in 4 as both [25,26,27,28]. Only 1 meta-analysis [29] (on psychotherapy) defined outcome as effect size on the BDI [30].…”
Section: Methodsmentioning
confidence: 99%
“…Four meta-analyses used the 17-items HDRS [20,25,26,27] to assess response, 1 meta-analysis used the 21-items HDRS [28] and 5 used either one or both versions of the HDRS (17 or 21 items) and/or the MADRS [15,16,17,18,19]. With respect to remission, cut-off scores on the post-treatment assessment of a depression severity scale were used.…”
Section: Methodsmentioning
confidence: 99%
“…Consequently, this normalization of NE neuron firing activity, together with 5-HT 2A receptor antagonism, may also prove beneficial in attenuating sexual dysfunctions which commonly plague SSRI users. The normal firing activity of LC and dorsal raphe neurons in the presence of increased 5-HT and NE synaptic availability may contribute to a decreased side effect profile and an increase in efficacy as reported with drugs that increase both 5-HT and NE synaptic availability (Danish University Antidepressant Group, 1990;Einarson et al, 1999;Poirier and Boyer, 1999;Silverstone and Ravindran, 1999).…”
Section: -Htmentioning
confidence: 99%
“…Moreover, even among patients who receive treatment, response and remission rates with current treatments are low, with over 50% failing to achieve remission in clinical trials of new antidepressants. [10][11][12][13][14][15] In six recent prospective observational community studies, [16][17][18][19][20][21] nonresponse rates ranged from 10 to 51%, partial response rates ranged from 11 to 45%, and remission rates ranged from 25 to 65%.…”
Section: Introductionmentioning
confidence: 99%