Comparison of Four Different Fuller’s Earth Formulations in Skin Decontamination

Roul, Annick; Le, Cong-Anh-Khanh; Gustin, Marie-Paule; Clavaud, Emmanuel; Verrier, Bernard; Pirot, Fabrice; Falson, Françoise

doi:10.1007/978-3-030-24009-7_8

Cited by 2 publications

(2 citation statements)

References 39 publications

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“…He found it better than most of other powders and pastes tested. This observation is particularly intriguing as Fuller's Earth is currently being investigated for its effectiveness in sulfur mustard decontamination, and is known as an effective decontaminant for lewisite exposure (Marrs, ; Roul et al, ; Taysse, Daulon, Delamanche, Bellier, & Breton, ).…”

Section: Work On Rapid Penetration Of Dichlorethyl Sulfide and Its Dementioning

confidence: 99%

Dermatotoxicology of sulfur mustard: Historical perspectives from World War I

Jiang

Maibach

2017

J of Applied Toxicology

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Sulfur mustard has been used as a chemical warfare agent for the past century. After its introduction by the Germans in World War I, investigators quickly began studying its impact on the human body including its deleterious effects on skin. This review focuses on two groups in particular who conducted experiments from 1917 to 1918: the United States Army at the American University Experiment Station Laboratories and Torald Sollmann at Western Reserve University. Through this work, these researchers proved far ahead of their time by anticipating dermatologic phenomena not described in the literature until later in the twentieth century. These include regional variation of percutaneous penetration, effect of vehicle on penetration and predicting immunologic contact urticaria. The work conducted by these researchers set the groundwork for much of twentieth century dermatotoxicology.

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Section: Work On Rapid Penetration Of Dichlorethyl Sulfide and Its Dementioning

confidence: 99%

Dermatotoxicology of sulfur mustard: Historical perspectives from World War I

Jiang

Maibach

2017

J of Applied Toxicology

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“…There are dry decontamination methods which have proven quite efficacious but are not readily available to the public in an emergency setting. For example, Fuller's Earth is an absorbing powder that generally allows for rapid and reliable decontamination (Roul et al, 2017). In addition, highly effective Decontamination Gel (DDGel) is a substance with a continuous thick consistency and can be applied to the skin, allowed to dry for 5 min and then peeled off (Cao et al, 2018).…”

Section: Introductionmentioning

confidence: 99%

A review of the efficacy of easily accessible dry decontaminants for human chemical contamination

Nandamuri

Feschuk

Maibach

2022

J of Applied Toxicology

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Soap and water are often considered the gold standard for dermal decontamination.However, recent systematic reviews have shown that these methods often result in incomplete decontamination and may even induce contaminant absorption due to the "wash-in" effect. Therefore, it is important to gain insight on other decontamination methods. A literature search was done using PubMed to find experimental studies relating to dry decontamination performed with readily available items. Seven studies met eligibility criteria, and the study model, dry decontaminant, method of dry decontamination, method of analyzing decontamination, and main conclusions from each study were extracted, summarized, and compared. Important conclusions include that all studies investigated found that dry decontamination yielded decreases in contamination. In addition, it was shown by multiple studies that not only the decontaminant, but the manner in which it is used (method used [blotting, rubbing, etc.], amount used, and whether decontamination instructions are provided to exposed individuals) is vital to success. Finally, in all four studies that investigated wet and dry decontamination combination protocols, combinations were more efficacious than dry decontamination alone. However, this means that dry improvised decontamination can be performed while waiting for the deployment and arrival of further formal decontaminants. These conclusions deserve consideration in the event that universal decontamination guidelines are designed. However, more studies are required in order to draw definitive conclusions regarding the important topic of dermal decontamination.

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Comparison of Four Different Fuller’s Earth Formulations in Skin Decontamination

Cited by 2 publications

References 39 publications

Dermatotoxicology of sulfur mustard: Historical perspectives from World War I

Dermatotoxicology of sulfur mustard: Historical perspectives from World War I

A review of the efficacy of easily accessible dry decontaminants for human chemical contamination

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