Comparison of freeze-dried tibialis anterior allograft and four-strand hamstring autograft in anterior cruciate ligament reconstruction

Issın, Ahmet; Öner, Ali Yusuf; Sofu, Hakan; Yurten, Hakan

doi:10.1016/j.aott.2018.08.001

Cited by 7 publications

(5 citation statements)

References 26 publications

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“…This study evaluated the two-year graft rupture rate for ACL reconstruction with fresh frozen allografts in a young, active population. Although non-irradiated allografts have been shown to be a safe alternative 30 , there remains concern and controversy due to high failure rates reported in the literature 15,18 . However, none of these studies have specifically looked at the allograft characteristics and their influence on ACL graft rupture rates.…”

Section: Discussionmentioning

confidence: 99%

“…Although nonirradiated allografts have been shown to be a safe alternative, 30 there remains concern and controversy attributed to the high failure rates reported in the literature. 14,17 However, none of these studies specifically examined the allograft characteristics and their influence on ACL graft rupture rates. This study suggests that the characteristics of the allograft play a significant role in rates of ACL graft rupture—in particular, the age and sex of the donor and the allograft morphology.…”

Section: Discussionmentioning

confidence: 99%

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Allograft Donor Characteristics Significantly Influence Graft Rupture After Anterior Cruciate Ligament Reconstruction in a Young Active Population

et al. 2020

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Background: Graft selection in anterior cruciate ligament (ACL) surgery can be difficult in a young active population given their high rates of reinjury. Allografts allow for control over graft size and reduce morbidity of autograft harvest. There are mixed results about the use of allograft in the literature; however, the influence of the properties of the allograft on outcomes has not been considered. Hypothesis: ACL reconstruction with allografts from older donors will have a higher rate of graft rupture when compared with allograft from young donors. Study Design: Cohort study; Level of evidence, 3. Methods: Patients (N = 211) aged 13 to 25 years underwent primary ACL reconstruction with fresh-frozen nonirradiated allograft. Four graft types were used: patellar tendon, Achilles tendon, tibialis anterior, and tibialis posterior. Details were collected on allograft donor age and sex. At a minimum of 24 months, patients were evaluated for any further injuries and subjective analysis by International Knee Documentation Committee (IKDC) questionnaire. Results: ACL graft rupture occurred in 23.5%. When grafts were separated into single strand (patellar and Achilles tendon) and multistrand (tibialis anterior and posterior), there was a significantly higher rate of reinjury in the single-strand grafts (29.9% vs 11%; P = .014). Grafts from female donors aged ≥50 years had significantly higher rates of ACL graft rupture (52.6%; P = .003) with increased odds by 6.7 times when compared with grafts from male donors aged <50 years. There was no significant difference in mean IKDC scores among the groups based on the age and sex of the allograft donor. Conclusion: The age and sex of the allograft donor and the morphology of the graft significantly influenced the rate of ACL graft rupture in young active patients. Tendons from female donors aged ≥50 years should be avoided given the higher rerupture rates as compared with male donors of any age and younger females.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Allograft Donor Characteristics Significantly Influence Graft Rupture After Anterior Cruciate Ligament Reconstruction in a Young Active Population

et al. 2020

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“…The autografts are commonly used for good functional outcomes [20] while donor muscle deficits of the hamstring and patellar tendon autografts are also well known [21]. Although allografts have potential advantages such as the absence of donor site morbidity, shorter operative times, improved cosmetics, and easier rehabilitation over autografts in ACL-R [22–24], functional scores of the ACL-R with a single loop freeze-dried irradiated tibialis anterior allograft were found similarly in four-strand hamstring autograft in nonathletic patients [25].…”

Section: Discussionmentioning

confidence: 99%

“…There is limited evidence on functional outcomes of the ACL-R with tibialis anterior allograft in the literature [22–25]. To our knowledge, limited number of studies evaluated only functional and subjective outcomes (IKDC and knee laxity) after the ACL-R using tibialis anterior allograft without the measurement of the muscle strength, hop distance, and proprioception.…”

Section: Discussionmentioning

confidence: 99%

Effects on Lower Extremity Neuromuscular Control Exercises on Knee Proprioception, Muscle Strength, and Functional Level in Patients with ACL Reconstruction

Kaya

Guney

Sayaca

et al. 2019

BioMed Research International

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Objective The purpose of this study was to determine the effects of lower extremity motor control exercises on knee proprioception, muscle strength, and functional level in patients with anterior cruciate ligament reconstruction (ACL-R). Materials and Methods Thirty-two of the 57 patients with ACL-R using tibialis anterior allografts were divided into two groups. Group I: lower extremity motor control exercises were added to the standard rehabilitation program. Group II: standard rehabilitation program was applied. Effects of lower extremity motor control exercises on quadriceps and hamstring muscles strength, knee joint position sense, and hop test were evaluated. Results There were no differences in muscle strength and endurance of the quadriceps and hamstring between the operative and nonoperative sides in Group I (p > 0.05) while there were significant differences in strength of the quadriceps and hamstring between the operative and nonoperative sides in Group II (p < 0.05). There were significant differences in the endurance of the quadriceps and hamstring and knee joint position sense at 15°, 45°, and 75° between the operative sides of the patients in both groups (p < 0.05). Conclusions The neuromuscular control exercises program was found to be more effective in reducing the difference in strength while the standard program was found to be more effective in reducing the difference in endurance between the operated knee and the other knee. This study revealed that neuromuscular control exercises should also be used to improve knee proprioception sense following ACL-R.

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“…24 There is a paucity of clinical studies analyzing storage methods stratified by sterilization techniques, however from the literature available, allograft storage method does not seem to be an important factor. 25…”

Section: Allograft Processing Storage and Outcomesmentioning

confidence: 99%

Allografts in soft-tissue knee surgery

Al-Hourani,

Haddad

2024

Bone Joint J

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Comparison of freeze-dried tibialis anterior allograft and four-strand hamstring autograft in anterior cruciate ligament reconstruction

Abstract: Level III, Therapeutic study.

Cited by 7 publications

References 26 publications

Allograft Donor Characteristics Significantly Influence Graft Rupture After Anterior Cruciate Ligament Reconstruction in a Young Active Population

Allograft Donor Characteristics Significantly Influence Graft Rupture After Anterior Cruciate Ligament Reconstruction in a Young Active Population

Effects on Lower Extremity Neuromuscular Control Exercises on Knee Proprioception, Muscle Strength, and Functional Level in Patients with ACL Reconstruction

Allografts in soft-tissue knee surgery

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