Comparison of fusion rate and clinical results between CaO-SiO2-P2O5-B2O3 bioactive glass ceramics spacer with titanium cages in posterior lumbar interbody fusion

Lee, Jae Hyup; Kong, Chang Bae; Yang, Jae Jun; Shim, Hee Jong; Koo, Ki Hyoung; Kim, Jeehyoung; Lee, Choon-Ki; Chang, Bong Soon

doi:10.1016/j.spinee.2016.07.531

Cited by 41 publications

(45 citation statements)

References 22 publications

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“…In the previous study, we reported the efficacy and safety of BGS-7 spacers compared with autograft using titanium cages in the patients who required 1-level posterior lumbar interbody fusion (PLIF). 18 The BGS-7 spacers showed similar fusion rates and clinical outcomes as autograft using titanium cages, and the number of adverse events after surgery was similar for both groups. However, the previous study evaluated radiologic status for only 6 months and 1 year after the surgery, thereby lacking long-term results.…”

mentioning

confidence: 76%

“…The previous study was performed for the subjects at 4 institutions to evaluate whether the BGS-7 spacer (NovoMax; CGBio Inc., Seongnam, Korea) implantation is noninferior to the implantation of titanium alloy (Ti-6Al-4V) cages (4CIS; Solco Biomedical, Seoul, Korea) filled with autologous bone in 1-level PLIF for a year. 18 The study was conducted between October 28, 2010, and September 13, 2013, and was approved by the Institutional Review Board (IRB) of each institution. This study was carried out to assess changes in bone fusion rate and clinical results at follow-up for at least 48 months from the patients of the previous study.…”

Section: Methodsmentioning

confidence: 99%

“…Additional materials including allograft, demineralized bone matrix, and bone morphogenetic proteins were not used for either group. 18 …”

Section: Methodsmentioning

confidence: 99%

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A Long-Term Follow-up, Multicenter, Comparative Study of the Radiologic, and Clinical Results Between a CaO-SiO2-P2O5-B2O3 Bioactive Glass Ceramics (BGS-7) Intervertebral Spacer and Titanium Cage in 1-Level Posterior Lumbar Interbody Fusion

Lee

Kim

Kang

et al. 2020

Clinical Spine Surgery: A Spine Publication

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mentioning

confidence: 76%

Section: Methodsmentioning

confidence: 99%

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A Long-Term Follow-up, Multicenter, Comparative Study of the Radiologic, and Clinical Results Between a CaO-SiO2-P2O5-B2O3 Bioactive Glass Ceramics (BGS-7) Intervertebral Spacer and Titanium Cage in 1-Level Posterior Lumbar Interbody Fusion

Lee

Kim

Kang

et al. 2020

Clinical Spine Surgery: A Spine Publication

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“…The use of enhanced titanium, additional bioactive glass ceramics, and other materials can reduce the rate of pseudoarthrosis. 31 Second, we need to preserve posterior support. Motion-preserving total disc replacement surgery showed more stable outcomes than the currently evaluated method 32 because of complete preservation of the posterior facet complex.…”

Section: How To Solve Issues and Gain Better Outcomesmentioning

confidence: 99%

Can posterior stand-alone expandable cages safely restore lumbar lordosis? A minimum 5-year follow-up study

Kim

Elbashier

Lee

et al. 2020

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Background: Lumbar lordosis (LL) can be restored, and screw-related complications may be avoided with the stand-alone expandable cage method. However, the long-term spinopelvic changes and safety remain unknown. We aimed to elucidate the long-term radiologic outcomes and safety of this technique. Methods: Data from patients who underwent multi-level stand-alone expandable cage fusion and 80 patients who underwent screw-assisted fusion between February 2007 and December 2012, with at least 5 years of follow-up, were retrospectively analyzed. Segmental angle and translation, short and whole LL, pelvic incidence, pelvic tilt, sacral slope (SS), sagittal vertical axis, thoracic kyphosis, and presence of subsidence, pseudoarthrosis, retropulsion, cage breakage, proximal junctional kyphosis (PJK), and screw malposition were assessed. The relationship between local, lumbar, and spinopelvic effects was investigated. The implant failure rate was considered a measure of procedure effectiveness and safety. Results: In total, 69 cases were included in the stand-alone expandable cage group and 150 cases in the control group. The stand-alone group showed shorter operative time (58.48±11.10 versus 81.43±13.75, P=.00028), lower rate of PJK (10.1% versus 22.5%, P=.03), and restoration of local angle (4.66±3.76 versus 2.03±1.16, P=.000079) than the control group. However, sagittal balance (0.01±2.57 versus 0.50 ±2.10, P=.07) was not restored, and weakness showed higher rate of subsidence (16.31% versus 4.85 %, P=.0018), pseudoarthrosis (9.92% versus 2.42%, P=.02), cage, and retropulsion (3.55% versus 0, P=.01) than the control group.Conclusions: Stand-alone expandable cage fusion can restore local lordosis; however, global sagittal balance was not restored. Furthermore, implant safety has not yet been proven.

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“…First, we need to use more stable and advanced materials for interbody fusion. The use of enhanced titanium, additional bioactive glass ceramics, and other materials can reduce the rate of pseudoarthrosis [32]. Second, we need to preserve posterior support.…”

Section: How To Solve Issues and Gain Better Outcomesmentioning

confidence: 99%

Can posterior stand-alone expandable cages safely restore lumbar lordosis? A minimum 5-year follow-up study

et al. 2020

View full text Add to dashboard Cite

Background Lumbar lordosis (LL) can be restored, and screw-related complications may be avoided with the stand-alone expandable cage method. However, the long-term spinopelvic changes and safety remain unknown. We aimed to elucidate the long-term radiologic outcomes and safety of this technique. Methods Data from patients who underwent multi-level stand-alone expandable cage fusion and 80 patients who underwent screw-assisted fusion between February 2007 and December 2012, with at least 5 years of follow-up, were retrospectively analyzed. Segmental angle and translation, short and whole LL, pelvic incidence, pelvic tilt, sacral slope (SS), sagittal vertical axis, thoracic kyphosis, and presence of subsidence, pseudoarthrosis, retropulsion, cage breakage, proximal junctional kyphosis (PJK), and screw malposition were assessed. The relationship between local, lumbar, and spinopelvic effects was investigated. The implant failure rate was considered a measure of procedure effectiveness and safety. Results In total, 69 cases were included in the stand-alone expandable cage group and 150 cases in the control group. The stand-alone group showed shorter operative time (58.48 ± 11.10 vs 81.43 ± 13.75, P = .00028), lower rate of PJK (10.1% vs 22.5%, P = .03), and restoration of local angle (4.66 ± 3.76 vs 2.03 ± 1.16, P = .000079) than the control group. However, sagittal balance (0.01 ± 2.57 vs 0.50 ± 2.10, P = .07) was not restored, and weakness showed higher rate of subsidence (16.31% vs 4.85%, P = .0018), pseudoarthrosis (9.92% vs 2.42%, P = .02), cage, and retropulsion (3.55% vs 0, P = .01) than the control group. Conclusions Stand-alone expandable cage fusion can restore local lordosis; however, global sagittal balance was not restored. Furthermore, implant safety has not yet been proven.

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Comparison of fusion rate and clinical results between CaO-SiO2-P2O5-B2O3 bioactive glass ceramics spacer with titanium cages in posterior lumbar interbody fusion

Abstract: In lumbar posterior interbody fusion surgery, CaO-SiO-PO-BO glass ceramics spacer showed a similar fusion rates and clinical outcomes compared with titanium cage.

Cited by 41 publications

References 22 publications

A Long-Term Follow-up, Multicenter, Comparative Study of the Radiologic, and Clinical Results Between a CaO-SiO2-P2O5-B2O3 Bioactive Glass Ceramics (BGS-7) Intervertebral Spacer and Titanium Cage in 1-Level Posterior Lumbar Interbody Fusion

A Long-Term Follow-up, Multicenter, Comparative Study of the Radiologic, and Clinical Results Between a CaO-SiO2-P2O5-B2O3 Bioactive Glass Ceramics (BGS-7) Intervertebral Spacer and Titanium Cage in 1-Level Posterior Lumbar Interbody Fusion

Can posterior stand-alone expandable cages safely restore lumbar lordosis? A minimum 5-year follow-up study

Can posterior stand-alone expandable cages safely restore lumbar lordosis? A minimum 5-year follow-up study

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