BACKGROUND In India, tuberculosis remains a major public health problem with high mortality and contributing significantly to world tuberculosis burden. Early diagnosis still remains a challenge and GeneXpert, a molecular test helps in detecting tuberculosis as early as within two hours. In the present study, role of GeneXpert for detecting MTB (mycobacterium tuberculosis) in bronchial lavage of tuberculosis suspects has been reported. Total 36 cases were reported and GeneXpert is found to be positive for MTB in 22 cases and compared with direct smear and cultures of BAL (bronchoalveolar lavage) fluid for MTB.