Comparison of Gingerols in Various Fractions and the Antioxidant Effects of Supercritical Fluid Extracts from Ginger

Lee, Eun‐Ju; Yang, Seun-Ah; Choi, Hee‐Don; Im, Hyo-Gwon; Whang, Key; Lee, In-Seon

doi:10.9721/kjfst.2011.43.4.469

Cited by 19 publications

(4 citation statements)

References 13 publications

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“…Several recent studies have shown that Z. latifolia is effective in reducing insulin resistance, suppressing hyperlipidemia, reducing blood glucose levels, exerting antiobesity effects, and preventing skin aging [21][22][23][24]. Lee et al [25] demonstrated that a methanol extract of Z. latifolia exhibits antiallergic effects through the inhibition of compound 48/80-induced degranulation and antigen-induced ß-hexosaminidase release in RBL-2H3 mast cells. Another study reported that one new flavonolignan, one flavone, and three flavonolignans were isolated as the active constituents from the ethyl acetate fraction of the aerial parts of Z. latifolia, and that tricin and its derivatives were the main components of Z. latifolia [26].…”

Section: Introductionmentioning

confidence: 99%

Enzyme-Treated Zizania latifolia Ethanol Extract Improves Liver-Related Outcomes and Fatigability

Ahn,

Kim,

Kim

et al. 2024

Foods

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Long-term hepatic damage is associated with human morbidity and mortality owing to numerous pathogenic factors. A variety of studies have focused on improving liver health using natural products and herbal medicines. We aimed to investigate the effect of enzyme-treated Zizania latifolia ethanol extract (ETZL), which increases the content of tricin via enzymatic hydrolysis, for 8 weeks on liver-related outcomes, lipid metabolism, antioxidant activity, and fatigue compared to a placebo. Healthy Korean adult males aged 19–60 years were randomized into ETZL treatment and placebo groups, and alcohol consumption was 24.96 and 28.64 units/week, respectively. Alanine transaminase, a blood marker associated with liver cell injury, significantly decreased after 8 weeks compared to the baseline in the ETZL treatment group (p = 0.004). After 8 weeks, the treatment group showed significant changes in the levels of high-density lipoprotein and hepatic steatosis index compared to the baseline (p = 0.028 and p = 0.004, respectively). ETZL treatment tended to reduce antioxidant-activity-related factors, total antioxidant status, and malondialdehyde, but there was no significant difference. In the multidimensional fatigue scale, ETZL treatment showed a significant reduction in general fatigue and total-fatigue-related values after 8 weeks compared to the baseline (p = 0.012 and p = 0.032, respectively). Taken together, the 8-week treatment of enzyme-treated Zizania latifolia ethanol extract demonstrated positive effects on liver-related outcomes, lipid metabolism, and mental fatigue without adverse effects on safety-related parameters.

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Section: Introductionmentioning

confidence: 99%

Enzyme-Treated Zizania latifolia Ethanol Extract Improves Liver-Related Outcomes and Fatigability

Ahn,

Kim,

Kim

et al. 2024

Foods

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“…생강은 특유의 맛과 향기를 지니고 있어 기호성이 좋은 향신료의 하나 로써 날 생강, 건 생강, 정유(absolute, oleoresin) 등이 생강 제품을 위 한 소재로 유통되고 있다 (Lee et al, 2011).…”

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Antioxidant Effect of Leaf, Stem, and Root Extracts of Zingiber officinale as Cosmetic Materials

Lee¹,

Kim²

2021

Asian J Beauty Cosmetol

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Purpose: In this study, we used Zingiber officinale (Z. officinale) leaf, stem, and root extracts to evaluate their potential as cosmetic materials. Methods: We measured DPPH radical-scavenging activity, total polyphenolic and flavonoid contents, ABTS radical scavenging activity, and SOD-like physiological activity to confirm the antioxidant effect to assess the potential of Z. officinale leaf, stem, and root extracts as cosmetic materials. Furthermore, the protective effect on oxidative stress caused by H 2 O 2 in HaCaT cells and proliferative effect in dermal papilla cells were assessed. Results: As a result of the antioxidant effect of Z. officinale leaf, stem, and root extracts, DPPH radical-scavenging activity was measured at a concentration of 400 μg/mL, and it was 88.78% in Z. officinale leaf extract, 70.12% in stem extract, and 65.52% in root extract. Total polyphenolic content was 170.22 μg/mL (leaf), 120.27 μg/mL (stem), and 146 μg/mL (root), whereas total flavonoid content was 98.52 μg/ mL (leaf), 70.26 μg/mL (stem), and 46.12 μg/mL (root). ABTS radical scavenging activity was measured at a concentration of 400 μg/mL, and it was 88.26% (leaf), 70.73% (stem), and 64.13% (root). Further, SOD-like physiological activity was 65.22% (leaf), 57.53% (stem), and 50.21% (root). The protective effect on oxidative stress caused by H 2 O 2 in HaCaT cells was 82.18% (leaf), 78.98% (stem), and 70.27% (root) at a concentration of 100 μg/mL. Our results confirmed that Z. officinale leaf extract has high protective effects on cell damage caused by H 2 O 2 , showing a 32% increase. Moreover, the proliferative effect in dermal papilla cells was 158.63% (leaf), 140.41% (stem), and 132.40% (root) when cells were cultured for 72 h at a concentration of 100 μg/mL. Conclusion: Thus, Z. officinale leaf extract has the highest antioxidant effect, HaCaT cell protective effect, and proliferative effect in dermal papilla cells, indicating a possibility to be developed as a cosmetic material.

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“…환류 냉각 추출법은 식물의 가용성 물질을 안정적으로 추출할 수 있으나 많은 용매가 필요하며 추출 과정에서 많은 시간이 소요되는 단점이 있다 (22). 또한, 초임계 유체 추출법은 기능성 물질을 추출하는 속도가 빠르며 용매의 소비량이 적고, 저온에서도 조작할 수 있어 열에 민감한 천연물질의 추출에 유용한 장점이 있지만 많은 비용이 드는 단점을 내포하고 있다 (23,24). 각 추출방법들이 가진 문제 점들을 보완하기 위한 적절한 대안으로 마이크로웨이브추 출(microwave-assisted extraction, MAE)이 주로 사용되고 있다 (25) Table 3).…”

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Optimization of microwave-assisted extraction process of Hordeum vulgare L. by response surface methodology

Lee¹,

Park²,

Lee³

2017

Korean Journal of Food Preservation

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This study attempted to find optimum extract range of active ingredient for barley sprouts (Hordeum vulgare L.). Extracts from Hordeum vulgare L. were made by microwave extraction method and total polyphenol content (TPC), total flavonoid content (TFC), DPPH radical scavenging activity (DPPH) were measured with extract of Hordeum vulgare L.. Response surface methodology (RSM) was applied to a extraction process, and central composite design (CCD) was also used for this process to examine the optimum condition. Independent variables (Xn) are concentration of ethanol (X1: 0, 25, 50, 75, 100%), microwave power (X2: 60, 120, 180, 240, 300 W), extraction time (X3: 4, 8, 12, 16, 20 min). Dependent variables (Yn) are TPC (Y1), TFC (Y2), DPPH radical scavenging (Y3). It is formed by sixteen conditions to extract. The R 2 value of dependent variables is ranged from 0.90 to 0.97 (p<0.05). Experiments values within the optimal range (40% of ethanol concentration, 120 W of microwave power, 18 min of extraction time) were 3.74 mg GAE/g (TPC), 3.00 mg RE/g (TFC), 35.43% (DPPH), respectively. Under the optimized conditions, predicted value showed no significant difference comparing with the experimental values.

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Comparison of Gingerols in Various Fractions and the Antioxidant Effects of Supercritical Fluid Extracts from Ginger

Cited by 19 publications

References 13 publications

Enzyme-Treated Zizania latifolia Ethanol Extract Improves Liver-Related Outcomes and Fatigability

Enzyme-Treated Zizania latifolia Ethanol Extract Improves Liver-Related Outcomes and Fatigability

Antioxidant Effect of Leaf, Stem, and Root Extracts of Zingiber officinale as Cosmetic Materials

Optimization of microwave-assisted extraction process of Hordeum vulgare L. by response surface methodology

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