Comparison of global left ventricular function using 20 phases with 10-phase reconstructions in multidetector-row computed tomography

Abstract

To compare the measurement of global left-ventricular (LV) function parameters of 64-slice multidetector-row computed tomography (MDCT) between 20- and 10-reconstruction phases. Fifty five patients with suspected or known coronary artery disease underwent 64-slice MDCT. LV end-diastolic volume (EDV), end-systolic volume (ESV), stroke volume (SV), and ejection fraction (EF) were measured from MDCT data sets using threshold-based volume segmentation and reconstruction at every 5% (20 phases) and 10% (10 phases) step through the R-R interval. These global functional parameters were compared to those obtained via two-dimensional transthoracic echocardiography (2D-TTE), considering the reference standard. The required time for CT data analysis was checked. Agreement for parameters of LV global function was determined using Pearson's correlation coefficient (r) and Bland-Altman analysis. LV volumes (EDV(-5%) 87.5 ± 17.1 ml, EDV(-10%) 87.7 ± 16.3 ml; ESV(-5%) 32.4 ± 10.6 ml, ESV(-10%) 31.9 ± 9.9 ml; SV(-5%) 55.1 ± 10.5 ml, SV(-10%) 55.8 ± 9.9 ml; mean ± SD) and EF (EF(-5%) 63.4 ± 6.2%, EF(-10%) 63.9 ± 5.8%) did not differ significantly between the 20- and 10 phase reconstructions, and evidenced good to excellent correlation (r = 0.786-0.896, all P < 0.001) with the 2D-TTE results. The mean required time for CT data analysis in the 20- and 10 phase reconstructions were 15.5 ± 4.0 and 7.3 ± 2.5 min. Within MDCT, using 10-phase image reconstruction is sufficient to evaluate LV volumes and EF, and is also more time-effective than 20-phase reconstruction.

Informatics in Radiology: Postprocessing Pitfalls in Using CT for Automatic and Semiautomatic Determination of Global Left Ventricular Function

“…The use of 5% instead of 10% increments has been described as yielding a higher accuracy and a more favorable comparison with MR imaging (3,22,23). However, recent comparative studies demonstrated that, although results were different with 5% intervals than with 10% intervals, the differences were not significant (24,25), so that phase reconstruction at 10% intervals is sufficient.…”

Kardiyak Morfoloji ve Fonksiyonların Multi Dedektör Bilgisayarlı Tomografi (MDBT) ile Değerlendirilmesi

“…[20] MDBT ile kardiyak fonksiyonların değerlendirilmesinde 10 faz (%10'luk intervallerden oluşan) ve 20 faz (%5'lik intervallerden oluşan) rekonstrüksiyon-ları birbirleriyle karşılaştırdıklarında, 10 faz ile yapılan incelemelerde sol ventrikül EF değerle-rinin kardiyak MR ve 3 boyutlu ekokardiyografiye göre daha düşük olduğunu belirtmişlerdir. Diğer taraftan, 10 faz veya 20 faz kullanılarak yapılan ölçümlerde ortaya çıkan farklılığın klinik olarak çok anlamlı olmadığını, 10 faz kullanıldığında görüntülerin daha kısa bir zamanda işlenebilmesi nedeniyle sol ventrikül volümü ve EF hesaplamasında tercih edilebileceğini belirten çalışmalar da mevcuttur [21].…”