Comparison of hematological and biochemical parameters in sheep naturally and persistently infected with a border disease virus

Abstract

In this study, we investigated the changes occurring in the activities of determining the biochemical and hematological parameters in persistently infected sheep with border disease virus (BDV) and control sheep. While cholesterol, aspartate aminotransferase, lactate dehydrogenase, high-density lipoprotein, and glucose parameters were found to be statistically different between control and BDV positive groups (p<0.01), total protein, alkaline phosphotase, creatine kinase, amylase, glucose, and high-density lipoprotein were found to be statistically different between control and persistently infected group (p<0.01). Interestingly, all groups were shown only mean corpuscular volume parameter was different (p<0.01). It was found that cholesterol, aspartate aminotransferase, amylase, high-density lipoprotein, and low-density lipoprotein parameters were different between PI and infected sheep (p<0.01). It was speculated that BDV might effect also the expression of low-density lipoprotein receptor and determination of the changes in BD and its clinical importance might contribute to the veterinarians and scientists studying in this area.

Haematological parameters in blood of maedi-visna virus-infected and uninfected sheep

“…Ballesteros et al (2010) reported that an increase in the Hematocrit and RBC value and Hgb concentration significantly different but they were not detected by any statistically significant differences in MCV, MCH, MCHC values between MVV positive and negative animals. RBC, MCH and Hgb has notspecific parameters for MVV or any diseases; therefore changes of these parameters could be associated with other conditions (Gazyagci et al, 2010). Lipecka et al (2010) reported that monocytes, macrophages lineage and mononuclear cells are the target for MVV (Lipecka et al, 2010).…”