Comparison of hematological findings in H1N1 infections with hematological findings in other viral agents

Abstract

Introduction:In this study, the hematologic findings of patients who were diagnosed with H1N1 virus infection and their effects on the course of the disease were reviewed.Method: Twenty-one children who received diagnosis of H1N1 infection were included in the study. Blood count results on days 1, 3 and 7 were examined. The frequency of the 1 st day hematologic findings of the patients was compared with those of 3 groups in the same age and the same number of patients. Time of onset of hematologic findings and prognostic effects were evaluated.Results: Seven of the 21 patients (33.3%) were female, and 14 (66.7%) were male. The mean age was 5.1 years. Seven patients (33.3%) had leukopenia, 3 (14.3%) had leukocytosis, and 4 (19%) had anemia. Nine patients (42.9%) had thrombocytopenia, and 1 patient (4.8%) had thrombocytosis. Lymphopenia was detected in 9 patients (42.9%), neutropenia in 3 (14.3%), and monocytosis in 8 patients (38.1%). Three patients who had underlying chronic disease or respiratory distress died during the follow-up period. Conclusion:In conclusion, more frequent and severe cytopenias seen in H1N1 infections are thought to cause the clinical presentation to be more severe.

Investigation of the incidence of vitamin B12 deficiency in leukopenia and neutropenia secondary to infection

“…Severe neutropenia in influenza outbreaks also plays an important role in the development of secondary bacterial infections. 10,11 In this patients, respiratory tract infections played an important role in the etiology. Since the patients had non-specific symptoms and the clinic had a mild course, no examinations were performed to determine the causative agent.…”