Comparison of Hyperbaric Levobupivacaine with Hyperbaric Bupivacaine in Unilateral Inguinal Hernia Operations Performed Under Spinal Anesthesia

Gözaydin, Orhan; Gülen, Güven; Atalan, Güneri; Kaydul, Mehmet

doi:10.5455/aces.20130724023552

Cited by 2 publications

(5 citation statements)

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“…These results show that baseline demographics were comparable for the two study groups. These demographic characteristics were similar to Hakan Erbay R et al 8 in 2010 and Gozaydin 9 in 2014 where authors assessed subjects with similar demographics as of the present study.…”

Section: Discussionsupporting

confidence: 86%

Comparison Of Hyperbaric Bupivacaine In Conventional Dose To Isobaric Levobupivacaine Used For Infra Umbilical Surgeries

Hasaraddi¹,

S²,

Vadigeri³

et al. 2022

Journal of Pharmaceutical Negative Results

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Background: For spinal anesthesia, levobupivacaine is considered an effective alternative anaesthetic agent to conventional bupivacaineowing to the faster recovery profile and lower probability of cardiovascular toxicity.Aim: To comparatively assess the analgesic and hemodynamic features of conventional dose of hyperbaric bupivacaine to isobariclevobupivacaine used for infra umbilical surgeries.Methods: The present clinical study included 120 subjects from ASA I and ASA II categories presented for elective infra umbilicalsurgeries and were randomly divided into 2 groups of 60 subjects each. Group, I subjects was given 0.5% hyperbaric bupivacaine atthe dose of 3ml, and Group II was given 0.5% isobaric levobupivacaine at the dose of 3ml. Hemodynamic parameters including SpO2,NIBP, and heart rates were assessed every 15 minutes till 2 hours postoperative. Side effects including nausea and vomiting,bradycardia, and hypotension were also evaluated.Results: Sensory block onset was slower in the levobupivacaine group and sensory block levels were comparable. For levobupivacaine,analgesia duration was significantly lower. With levobupivacaine, shorter motor blockade duration and slower motor blockade onsetwere seen. Complete motor blockade was seen in all subjects. Concerning hemodynamic parameters, lesser incidence of bradycardiaand hypotension and high cardiovascular stability. No incidence of PDPH, shivering, nausea, or vomiting was seen in any subject.Conclusion: The present study concludes that significantly similar effects concerning analgesia duration are seen with Bupivacaine aswith levobupivacaine. However, Bupivacaine showed better cardiovascular stability making Levobupivacaine use successful for lowerabdominal surgeries.

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Section: Discussionsupporting

confidence: 86%

Comparison Of Hyperbaric Bupivacaine In Conventional Dose To Isobaric Levobupivacaine Used For Infra Umbilical Surgeries

Hasaraddi¹,

S²,

Vadigeri³

et al. 2022

Journal of Pharmaceutical Negative Results

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“…Gozaydin et al [6] concluded that the mean time for Grade 4 bromage scale for levobupivacaine is 11 min which is comparable to this study, in spite of usage of hyperbaric levobupivacaine in that study.…”

Section: Dikkala and Guntreddysupporting

confidence: 85%

“…This study is in comparison with the study conducted by Gozaydin et al [6] which showed the mean time to achieve maximum level of sensory blockade with hyperbaric levobupivacaine is 11 min.…”

Section: Dikkala and Guntreddysupporting

confidence: 56%

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A Comparative Study Between 0.5% Levobupivacaine and 0.75% Ropivacaine in Patients Undergoing Elective Lower Limb Surgeries Under Subarachnoid Block

DIKKALA,

GUNTREDDY

2023

Asian J Pharm Clin Res

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Objective: The aim of the study was to compare the efficacy of 0.5% levobupivacaine and 0.75% ropivacaine after intrathecal administration in elective lower limb surgeries. Methods: A prospective, randomized, controlled, and double-blind study was conducted on 100 patients undergoing elective lower limb surgeries under subarachnoid block using 0.5% levobupivacaine and 0.75% ropivacaine. Results: Demographic characteristics of both groups are comparable. It is observed the onset of sensory blockade is earlier in ropivacaine group, Grade 4 bromage scale motor blockade onset is shorter in levobupivacaine and most of the parameters are comparable between two groups. Duration of sensory blockade is more in ropivacaine when compared to levobupivacaine. Levobupivacaine is more cardiostable with stable hemodynamic profile compared to ropivacaine. Conclusion: Levobupivacaine is more cardiostable with stable hemodynamic profile compared to ropivacaine.

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Comparison of Hyperbaric Levobupivacaine with Hyperbaric Bupivacaine in Unilateral Inguinal Hernia Operations Performed Under Spinal Anesthesia

Cited by 2 publications

References 0 publications

Comparison Of Hyperbaric Bupivacaine In Conventional Dose To Isobaric Levobupivacaine Used For Infra Umbilical Surgeries

Comparison Of Hyperbaric Bupivacaine In Conventional Dose To Isobaric Levobupivacaine Used For Infra Umbilical Surgeries

A Comparative Study Between 0.5% Levobupivacaine and 0.75% Ropivacaine in Patients Undergoing Elective Lower Limb Surgeries Under Subarachnoid Block

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