Comparison of image-based three-dimensional treatment planning using Acuros^TM BV and AAPM TG-43 algorithm for intracavitary brachytherapy of carcinoma cervix

Abstract

AimTo compare the image-based three-dimensional treatment planning using AcurosTM BV and AAPM TG-43 algorithm for intracavitary brachytherapy of carcinoma cervix.Materials and methodsTwenty-seven patients with cancer cervix, stage IIB or IIIB with vaginal involvement limited to the upper third of the vagina was included into the study. Intracavitary treatments with the patient in this study done with computed tomography and magnetic resonance imaging compatible ring applicator. Groupe European de Curietherapie and European Society for Therapeutic Radiology and Oncology recommended doses to target volumes and organs at risk compared using dose volume histogram.ResultsThe mean value of Point ‘A’ dose was compared between AcurosTM BV and TG-43, which indicates 0·13% difference. The differences in the mean dose to gross tumour volume for various volumes are V100% 0·28%, V150% 1·22% and V200% 1·03%; all volumes showed small difference but statistical significant (p<0·05). The mean dose of high-risk clinical target volume (HRCTV) D90 using AcurosTM BV was 8·47 Gy, which was 1·63% less compared with TG-43. The mean point A dose using AcurosTM BV is 1·04 times the dose to D90 of mean HRCTV. The same difference was observed in comparison with TG43. D2cc and D0·1cc of the bladder, rectum and sigmoid showed a statistically significant difference (p<0·05) in comparison with TG-43.ConclusionThe differences in dosimetric parameters between the AcurosTM BV and TG-43 proved to be statistically significant. The difference is very small, and they are clinically insignificant.

Review on Treatment Planning Systems for Cervix Brachytherapy (Interventional Radiotherapy): Some Desirable and Convenient Practical Aspects to Be Implemented from Radiation Oncologist and Medical Physics Perspectives

“…Due to its clinical relevance, the cervix treatments were among the first to be analysed from the perspective of MBDCA. Retrospective assessments of the relevance of heterogeneities in the case of the conventional Manchester system plans have been performed [ 49 , 50 , 51 ]. A small impact on the TG-43 calculated dosimetric parameters was reported, observing minor changes in Point A and B doses and the D 2cc and D 90 volumetric parameters.…”

The dosimetric effect of variations in source position on treatments using Leipzig-style brachytherapy skin applicators

“…Initial dose calculations were undertaken using the Acuros BV dose calculation algorithm (version 1.7) in the BrachyVision planning software (Varian Medical Systems, Palo Alto, California) using a 0.5 mm × 0.5 mm × 0.5 mm grid size and a source strength of 40,700 cGy cm 2 h −1 . Acuros is a grid-based Boltzmann solver (GBBS) algorithm which has been shown to be superior to TG-43 in situations where there are significant inhomogeneities or a lack of full scatter conditions [22][23][24][25]. Based on the GEC-ESTRO guidelines for skin brachytherapy [26] a depth of 3 mm was selected for dose prescription and a reference point was inserted at this depth, directly below the axis of symmetry of the applicator.…”

Contrastive Study of the Images of Figures of Ladies in the Tang Dynasty and Japanese Ukiyoe Beauty Paintings

“…The social origin of the painting has created the "sorrowful" and "traceful" emotional expression and the national aesthetic model of beauty paintings. Traditional Chinese beauty paintings do not simply take beauty as the only pursuit, but rather focus on the expression of the charm of the characters [23], emphasizing the feelings that the inner beauty of the characters brings to the viewer.…”