Comparison of image quality and radiation dose of different pulmonary CTA protocols on a 128-slice CT: high-pitch dual source CT, dual energy CT and conventional spiral CT

Zordo, Tobias De; Lutterotti, K. von; Dejaco, Christian; Soegner, P; Frank, R; Aigner, Friedrich; Klauser, Andrea; Pechlaner, Christoph; Schoepf, U. Joseph; Jaschke, Werner; Feuchtner, Gudrun

doi:10.1007/s00330-011-2251-y

Cited by 62 publications

(38 citation statements)

References 30 publications

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“…However, the above mentioned lower image quality in group 1 did not reach statistical significance (p = 0.076). The overall interobserver agreement of 80.0 % emphasizes the results of previous CTPA investigations [17].…”

Section: Discussionsupporting

confidence: 67%

“…Zordo et al estimated a mean radiation dose of 4.2 mSV in their dual-energy group when using 2nd generation DSCT [17]. This is the first study investigating the radiation dose of dual-energy CTPA with third generation DSCT.…”

Section: Discussionmentioning

confidence: 91%

“…In a first phantom study using 1st and 2nd generation DSCT scanners, Schenzle et al showed no additional dose burden or compromises in image quality in comparison to a 120 kV standard protocol [19]. Zordo et al systematically compared the radiation dose of second generation DSCT in single-energy mode with dual-energy mode (100/Sn140 kV) and conventional single-source single-energy 128-MDCT at 120 kV and 100 kV in 321 patients with suspected pulmonary embolism [17]. Their study revealed a significantly lower radiation dose of dual-energy acquisition when compared to conventional single-energy 128-MDCT at 120 kV.…”

Section: Discussionmentioning

confidence: 99%

“…The effective radiation dose of current conventional SSCT protocols for CTPA is estimated at 3.58 to 5.81 mSv when using a conversion factor of 0.018 mSv/mGycm [17,19]. Zordo et al estimated a mean radiation dose of 4.2 mSV in their dual-energy group when using 2nd generation DSCT [17].…”

Section: Discussionmentioning

confidence: 99%

“…Some data regarding the dose and image quality of CTPA of first and second generation DSCT scanners is available [16,17]. However, the potential of the latest (third) generation scanners to further decrease radiation dose while maintaining image quality has scarcely been assessed so far [18].…”

Section: Introductionmentioning

confidence: 99%

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Diagnosis of Pulmonary Artery Embolism: Comparison of Single-Source CT and 3rd Generation Dual-Source CT using a Dual-Energy Protocol Regarding Image Quality and Radiation Dose

Petritsch¹,

Kosmala²,

Gassenmaier³

et al. 2017

Fortschr Röntgenstr

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ZUSAMMENFASSUNGZiel Das Potential der Dritt-Generation Dual-Source CT (DSCT) in der Lungenemboliediagnostik wurde bis dato noch nicht ausführlich untersucht. Ziel dieser Studie war es, Strahlendosisparameter sowie subjektive und objektive Bildqualität des aktuellsten DSCT Scanners im Single-Energy und Dual-Energy (DE) Modus mit einem herkömmlichen pulmonalen Standard CTA Protokoll am 64-Zeilen CT (SSCT) zu vergleichen. This document was downloaded for personal use only. Unauthorized distribution is strictly prohibited. Material und Methoden▪ Die Dual-Energy CT bietet potentiell zusätzliche Informationen durch die Erstellung von farbcodierten Jod-Karten. ABSTR AC TPurpose To compare radiation dose, subjective and objective image quality of 3 rd generation dual-source CT (DSCT) and dual-energy CT (DECT) with conventional 64-slice singlesource CT (SSCT) for pulmonary CTA.Materials and Methods 180 pulmonary CTA studies were performed in three patient cohorts of 60 patients each. Group 1: conventional SSCT 120 kV (ref.); group 2: single-energy DSCT 100 kV (ref.); group 3: DECT 90/Sn150 kV. CTDIvol, DLP, effective radiation dose were reported, and CT attenuation (HU) was measured on three central and peripheral levels. The signal-to-noise-ratio (SNR) and contrast-to-noise-ratio (CNR) were calculated. Two readers assessed subjective image quality according to a five-point scale.Results Mean CTDIvol and DLP were significantly lower in the dual-energy group compared to the SSCT group (p < 0.001 [CTDIvol]; p < 0.001 [DLP]) and the DSCT group (p = 0.003 [CTDIvol]; p = 0.003 [DLP]), respectively. The effective dose in the DECT group was 2.79 ± 0.95 mSv and significantly smaller than in the SSCT group (4.60 ± 1.68 mSv, p < 0.001) and the DSCT group (4.24 ± 2.69 mSv, p = 0.003). The SNR and CNR were significantly higher in the DSCT group (p < 0.001).Subjective image quality did not differ significantly among the three protocols and was rated good to excellent in 75 % (135/180) of cases with an inter-observer agreement of 80 %.Conclusion Dual-energy pulmonary CTA protocols of 3 rd generation dual-source scanners allow for significant reduction of radiation dose while providing excellent image quality and potential additional information by means of perfusion maps. Key Points:▪ Dual-energy CT with 90/Sn150 kV configuration allows for significant dose reduction in pulmonary CTA. ▪ Subjective image quality was similar among the three evaluated CT-protocols (64-slice SSCT, single-energy DSCT, 90/Sn150 kV DECT) and was rated good to excellent in 75% of cases.

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Section: Discussionsupporting

confidence: 67%

Section: Discussionmentioning

confidence: 91%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Diagnosis of Pulmonary Artery Embolism: Comparison of Single-Source CT and 3rd Generation Dual-Source CT using a Dual-Energy Protocol Regarding Image Quality and Radiation Dose

Petritsch¹,

Kosmala²,

Gassenmaier³

et al. 2017

Fortschr Röntgenstr

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Control study of low tube voltage computed tomography angiography (CTA) and digital subtraction angiography (DSA) in diagnosing intracranial micro‐aneurysm

Duan

Liu

et al. 2017

Int J Imaging Syst Tech

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The aim of this study was to investigate the diagnostic values of low tube voltage cerebral computed tomography (CT) angiography (L‐CTA, 100 kV) of intracranial micro‐aneurysms (IMA, maximum diameter ≤3 mm). The clinical and imaging data of a total of 59 IMA patients confirmed by 3D rotational angiography (3DRA) or surgery were retrospectively analyzed; their L‐CTA data were compared with those of IMA and 3DRA so as to investigate the diagnostic sensitivity, specificity, and accuracy of IMA, as well as to objectively evaluate the related radiation dose. Based on the results of 3DRA, 65 cases of IMA and a total of 70 aneurysms, including 65 micro‐aneurysms, were found in the 59 cases. L‐CTA detected a total of 64 IMA, including six multiple cases of IMA, as well as three false positive cases and four missed cases. Compared with the 3DRA (gold standard), the diagnostic sensitivity, specificity, and accuracy of L‐CTA toward IMA were 93.85%, 99.56%, and 99.08%, respectively, and the associations of aneurysm size measured by L‐CTA and 3DRA were good. Compared with conventional CTA, the effective dose of L‐CTA was reduced by 36.23%. L‐CTA has high diagnostic sensitivity toward IMA, and can effectively reduce the radiation dose, so it is worth implementing.

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Ventilation/Perfusion SPECT Imaging Diagnosing PE and Other Cardiopulmonary Diseases

Bajc

Lindqvist

2020

Clinical Nuclear Medicine

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Comparison of image quality and radiation dose of different pulmonary CTA protocols on a 128-slice CT: high-pitch dual source CT, dual energy CT and conventional spiral CT

Cited by 62 publications

References 30 publications

Diagnosis of Pulmonary Artery Embolism: Comparison of Single-Source CT and 3rd Generation Dual-Source CT using a Dual-Energy Protocol Regarding Image Quality and Radiation Dose

Diagnosis of Pulmonary Artery Embolism: Comparison of Single-Source CT and 3rd Generation Dual-Source CT using a Dual-Energy Protocol Regarding Image Quality and Radiation Dose

Control study of low tube voltage computed tomography angiography (CTA) and digital subtraction angiography (DSA) in diagnosing intracranial micro‐aneurysm

Ventilation/Perfusion SPECT Imaging Diagnosing PE and Other Cardiopulmonary Diseases

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