Comparison of image quality between spectral photon-counting CT and dual-layer CT for the evaluation of lung nodules: a phantom study

Si‐Mohamed, Salim; Greffier, Joël; Miailhes, Jade; Boccalini, Sara; Rodesch, Pierre‐Antoine; Vuillod, Aurélie; Werf, Niels van der; Dabli, Djamel; Racine, Damien; Rotzinger, David C.; Becce, Fabio; Yagil, Yoad; Coulon, Philippe; Vlassenbroek, Alain; Boussel, Loîc; Beregi, Jean‐Paul; Douek, Philippe

doi:10.1007/s00330-021-08103-5

Cited by 33 publications

(25 citation statements)

References 25 publications

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“…The systems’ spatial resolution performance assessment also showed considerable differences. Of note, the SPCCT provided markedly improved spatial resolution over the conventional CT system, on par with recent previous investigations [ 23 , 24 , 25 ]. Because they do not require septa physically separating detector elements, PCDs can be manufactured in much smaller dimensions, in the order of 100–500 µm, overcoming one of EIDs’ major limitations: dose-inefficiency at small detector element size.…”

Section: Discussionsupporting

confidence: 82%

“…NPS analysis confirmed the significantly lower noise magnitude of SPCCT, which is an anticipated improvement [ 23 ] owing to the ability of PCDs to void electronic noise almost completely and showed differences in noise texture, with NPS peaks occurring at a significantly higher spatial frequency with the SPCCT. Higher frequency peak visually translates to “finer” noise texture, facilitating lesion detection [ 17 ], especially when small and with low object-to-background contrast, such as the lipid-rich plaques we simulated in the frequency domain with our task-based assessment.…”

Section: Discussionmentioning

confidence: 88%

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Performance of Spectral Photon-Counting Coronary CT Angiography and Comparison with Energy-Integrating-Detector CT: Objective Assessment with Model Observer

et al. 2021

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Aims: To evaluate spectral photon-counting CT’s (SPCCT) objective image quality characteristics in vitro, compared with standard-of-care energy-integrating-detector (EID) CT. Methods: We scanned a thorax phantom with a coronary artery module at 10 mGy on a prototype SPCCT and a clinical dual-layer EID-CT under various conditions of simulated patient size (small, medium, and large). We used filtered back-projection with a soft-tissue kernel. We assessed noise and contrast-dependent spatial resolution with noise power spectra (NPS) and target transfer functions (TTF), respectively. Detectability indices (d’) of simulated non-calcified and lipid-rich atherosclerotic plaques were computed using the non-pre-whitening with eye filter model observer. Results: SPCCT provided lower noise magnitude (9–38% lower NPS amplitude) and higher noise frequency peaks (sharper noise texture). Furthermore, SPCCT provided consistently higher spatial resolution (30–33% better TTF10). In the detectability analysis, SPCCT outperformed EID-CT in all investigated conditions, providing superior d’. SPCCT reached almost perfect detectability (AUC ≈ 95%) for simulated 0.5-mm-thick non-calcified plaques (for large-sized patients), whereas EID-CT had lower d’ (AUC ≈ 75%). For lipid-rich atherosclerotic plaques, SPCCT achieved 85% AUC vs. 77.5% with EID-CT. Conclusions: SPCCT outperformed EID-CT in detecting simulated coronary atherosclerosis and might enhance diagnostic accuracy by providing lower noise magnitude, markedly improved spatial resolution, and superior lipid core detectability.

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Section: Discussionsupporting

confidence: 82%

Section: Discussionmentioning

confidence: 88%

Performance of Spectral Photon-Counting Coronary CT Angiography and Comparison with Energy-Integrating-Detector CT: Objective Assessment with Model Observer

et al. 2021

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“…This comparison was performed on VMIs and iodine maps reconstructed only with Filtered Back Projection (FBP) using parameters and dose levels close to those used in clinical practice for DECT examinations of the abdomen. Spectral performance was studied using a task-based image quality assessment (noise magnitude, noise texture, spatial resolution and detectability of contrastenhanced lesions) often used in conventional single-energy CT (SECT) (13)(14)(15)(16)(17)(18)(19)(20)(21)(22) and increasingly used in DECT (12,23,24). However, this study did not compare the spectral performance of these platforms with the use of IR (hybrid or advanced/partial Model-based IR) algorithms used in clinical practice.…”

Section: Introductionmentioning

confidence: 99%

Comparison of virtual monoenergetic imaging between a rapid kilovoltage switching dual-energy computed tomography with deep-learning and four dual-energy CTs with iterative reconstruction

Greffier¹,

Guiu²,

Frandon³

et al. 2022

Quant Imaging Med Surg

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“…(e) Dose efficiency The advantages described above of PCD over ID lead to a better dose efficiency, as demonstrated by several studies [9,[20][21][22][23]. The effect of this dose efficiency can be either to produce the same image quality for the same dose or to investigate new protocols.…”

Section: (D) Reduction Of Beam Hardeningmentioning

confidence: 98%

“…In addition, iterative reconstruction can decrease noise levels in reconstructed CT images. Combined with the emergence of iterative reconstruction, PCD-CT enables either the reconstruction with a larger matrix (1024 × 1024 or 2048 × 2048) or the efficiency of ultra-low dose protocols [9,22].…”

Section: (D) Reduction Of Beam Hardeningmentioning

confidence: 99%

Spectral Photon-Counting CT Technology in Chest Imaging

Si‐Mohamed

Miailhes

Rodesch

et al. 2021

JCM

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The X-ray imaging field is currently undergoing a period of rapid technological innovation in diagnostic imaging equipment. An important recent development is the advent of new X-ray detectors, i.e., photon-counting detectors (PCD), which have been introduced in recent clinical prototype systems, called PCD computed tomography (PCD-CT) or photon-counting CT (PCCT) or spectral photon-counting CT (SPCCT) systems. PCD allows a pixel up to 200 microns pixels at iso-center, which is much smaller than that can be obtained with conventional energy integrating detectors (EID). PCDs have also a higher dose efficiency than EID mainly because of electronic noise suppression. In addition, the energy-resolving capabilities of these detectors allow generating spectral basis imaging, such as the mono-energetic images or the water/iodine material images as well as the K-edge imaging of a contrast agent based on atoms of high atomic number. In recent years, studies have therefore been conducted to determine the potential of PCD-CT as an alternative to conventional CT for chest imaging.

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Comparison of image quality between spectral photon-counting CT and dual-layer CT for the evaluation of lung nodules: a phantom study

Cited by 33 publications

References 25 publications

Performance of Spectral Photon-Counting Coronary CT Angiography and Comparison with Energy-Integrating-Detector CT: Objective Assessment with Model Observer

Performance of Spectral Photon-Counting Coronary CT Angiography and Comparison with Energy-Integrating-Detector CT: Objective Assessment with Model Observer

Comparison of virtual monoenergetic imaging between a rapid kilovoltage switching dual-energy computed tomography with deep-learning and four dual-energy CTs with iterative reconstruction

Spectral Photon-Counting CT Technology in Chest Imaging

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