To increase meat production at a level parallel to meet the demand of the increasing world population in recent years, reproductive management in farm animals must be successful. In order to reach the desired level of fertility in sheep, particularly starting with the non-prolific breeds, anoestrus period applications should be carried out effectively. In this study, different doses of equine chorionic gonadotropin were applied to determine the effective eCG dose for underwent estrus synchronization with progesterone in anoestrus Kangal ewes whose milk and wool yield has been completely abandoned by the breeder for various reasons and whose only economic benefit is lamb production. A total of 225 Kangal Akkaraman Sheep breeds, 2 years old, with a body condition score of 2.5-3.5 and an average weight of 40-50 kg, were included in the study. In line with this purpose, ewes were divided into 3 groups, containing 75 primiparous sheep. A vaginal sponge containing progesterone was inserted into the animals in all groups on day 0. Seven days after this application (on the 7th day), vaginal sponges were removed and Prostaglandin F2α (PGF2α) was applied. When the vaginal sponge was removed and the PGF2α was administered, 400 IU of eCG was given to animals in Group 1 (n:75), 500 IU of eCG was administrated to animals in Group 2 (n:75), and 600 IU of eCG was injected to the ewes in Group 3. The effectiveness of different doses of eCG application on reproductive parameters such as estrous rate, pregnancy rate, multiple pregnancy rate, and the number of offspring was evaluated. While no statistical difference could be determined between the groups in terms of the stated reproductive parameters, numerically more offspring were obtained in the group in which eCG was applied at a low rate (Group 1). In the light of this information, it is concluded that 400 IU eCG can be as effective as 600 IU eCG in sexual stimulation of Kangal ewes in anestrus.