Comparison of IMRT and VMAT plans with different energy levels using Monte-Carlo algorithm for prostate cancer

Onal, Cem; Arslan, G.; Parlak, Eda; Sonmez, Serhat

doi:10.1007/s11604-014-0291-3

Cited by 20 publications

(9 citation statements)

References 35 publications

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“…The decrease in monitor units for the 10 MV plans indicates that the higher energy beams were able to achieve equivalent target dose coverage more efficiently than the lower energy beams. This reduction in MUs for higher energy beams agrees with results found by other groups that have compared 6 MV with 10, 15, and 18 MV VMAT and IMRT plans for prostate and cervix cancer cases 34, 35, 36…”

Section: Discussionsupporting

confidence: 90%

Energy‐dependent OAR sparing and dose conformity for total marrow irradiation of obese patients

Cherpak

Monajemi

Chytyk-Praznik

et al. 2018

J Applied Clin Med Phys

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PurposeTo investigate the effect on target coverage and organs at risk sparing by using 10 versus 6 MV for VMAT total marrow irradiation of obese patients.Methods and MaterialsTwenty‐six total marrow irradiation, TMI, treatment plans delivered between December 2014 and June 2017 were reviewed and 10 were chosen for replanning based on patient characteristics and plan metrics. Beam geometry and isocenter placement were conserved, energy was changed from 6 to 10 MV and plans were reoptimized. Resulting dose distributions were compared to original plans to evaluate any potential advantage of choosing one energy over the other.ResultsTarget coverage and total monitor units were consistent between the 6 and 10 MV plans when averaged over all ten patients. Improvement in the conformity index (−11.0%, P = 0.009) when using 10 MV was statistically significant compared to the 6 MV plans. Volumes of normal tissue receiving 50%, 75%, and 90% Rx all decreased for the 10 MV plans compared to the original 6 MV plans. The mean dose to individual OARs decreased significantly for all investigated structures except for the lenses, oral cavity, and genitalia. The largest decreases in Dmean were found for the rectum (22.4%, P = 0.004) and bladder (18.1%, P = 0.005). The three highest priorities for sparing during plan optimization (lungs, liver, and heart), showed decreases of 7.6%, 16.1%, and 13.0%.ConclusionsUse of a higher energy 10 MV beam provided similar dose to target while achieving increased OAR and normal tissue sparing for the patients reviewed in this study.

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Section: Discussionsupporting

confidence: 90%

Energy‐dependent OAR sparing and dose conformity for total marrow irradiation of obese patients

Cherpak

Monajemi

Chytyk-Praznik

et al. 2018

J Applied Clin Med Phys

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“…For small bowel, the Sale study reported that there was no significant reduction in the volume of small bowel receiving lower doses in VMAT plans. Onal et al (34) also reported that there was no significant irradiation dose differences about D50 and Dmax between IMRT and VMAT in sigmoid colon.…”

Section: Discussionmentioning

confidence: 95%

Dosimetric comparison of intensity‐modulated radiotherapy and volumetric‐modulated arc radiotherapy in patients with prostate cancer: a meta‐analysis

Ren

Sun

Liu

et al. 2016

J Applied Clin Med Phys

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Intensity‐modulated radiotherapy (IMRT) and volumetric‐modulated arc therapy (VMAT) are two main radiotherapy techniques. The aim of this study is to explore which is the preferred technique in prostate treatment through the related publications and meta‐analysis. Two authors independently identified all relevant articles available regarding eligibility criteria on PubMed, Embase, and Cochrane Library databases until December 2015. Publication bias was evaluated with funnel plot, and statistical analyses were performed with Stata software. P<0.05 was thought statistically significant. Ten studies comprised a total of 110 patients; in total 110 IMRT plans and 110 VMAT plans that were included in this study. V40, V60, and V70 of rectum were significantly decreased in VMAT than in IMRT. However, V50 of rectum and V40, V50, V60, V70 of bladder had no statistical differences between IMRI and VMAT plans. Compared with IMRT, the treatment time and MUs of VMAT were significantly lower. VMAT protects rectum better than IMRT and improves the delivery efficiency. VMAT may be the preferred modality for treating prostate cancer.PACS number(s): 87.55. D‐

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“…Onal et al . [ 27 ] also compared IMRT and VMAT plans with different energy levels 6, 10, and 15 MV using Monte-Carlo algorithm for prostate cancer. They found the significant difference only in number of MUs for 10 MV and 6 MV plans, as they did not calculate GM, EVI, and low dose volume of normal tissue.…”

Section: Discussionmentioning

confidence: 99%

The dosimetric impact of different photon beam energy on RapidArc radiotherapy planning for cervix carcinoma

Kumar¹,

Yadav²,

Raman³

et al. 2015

J Med Phys

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The main purpose of this study is to know the effect of three different photon energies viz., 6, 10, and 15 mega voltage (MV) on RapidArc (RA) planning for deep-seated cervix tumor and to develop clinically acceptable RA plans with suitable photon energy. RA plans were generated for 6, 10, and 15 MV photon energies for twenty patients reported with cervix carcinoma. RA plans were evaluated in terms of planning target volume (PTV) coverage, dose to organs at risk (OARs), conformity index (CI), homogeneity index (HI), gradient measure, external volume index of dose distribution produced, total number of monitor units (MUs), nontumor integral dose (ID), and low dose volume of normal tissue. A two-sample paired t-test was performed to compare the dosimetric parameters of RA plans. Irrespective of photon energy used for RA planning, plans were dosimetrically similar in terms of PTV coverage, OARs sparing, CI and HI. The numbers of MUs were 13.4 ± 1.4% and 18.2 ± 1.5% higher and IDs were 2.7 ± 0.8% and 3.7 ± 0.9% higher in 6 MV plans in comparison to that in the 10 and 15 MV plans, respectively. V1Gy, V2Gy, V3Gy, and V4Gy were higher in 6 MV plans in comparison to that in 10 and 15 MV plans. Based on this study, 6 MV photon beam is a good choice for RA planning in case of cervix carcinoma, as it does not deliver additional exposure to patients caused by photoneutrons produced in high energy beams.

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Comparison of IMRT and VMAT plans with different energy levels using Monte-Carlo algorithm for prostate cancer

Abstract: VMAT plans were found to be dosimetrically equivalent to IMRT plans for prostate cancer patients, with better rectum and bladder sparing and fewer MUs required.

Cited by 20 publications

References 35 publications

Energy‐dependent OAR sparing and dose conformity for total marrow irradiation of obese patients

Energy‐dependent OAR sparing and dose conformity for total marrow irradiation of obese patients

Dosimetric comparison of intensity‐modulated radiotherapy and volumetric‐modulated arc radiotherapy in patients with prostate cancer: a meta‐analysis

The dosimetric impact of different photon beam energy on RapidArc radiotherapy planning for cervix carcinoma

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