Comparison of Incidence, Mortality and Treatment of Acute Myocardial Infarction in Hospitals in Japan and China.

Liu, Zhuo; Honma, Tomoki; Kaku, Nobuo

doi:10.2739/kurumemedj.39.279

Cited by 6 publications

(3 citation statements)

References 2 publications

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“…In China, reports of short-term mortality after AMI range from 8.1% to 18% in hospital-based studies. 45,46 Our findings are consistent with an international study that identified a higher age-adjusted 28-day case fatality rate among AMI patients from China compared with AMI patients in Canada. 47 Nevertheless, the higher early mortality among Chinese patients cannot be fully explained by increased cardiovascular risk factors and advanced age at the time of presentation.…”

Section: Discussionsupporting

confidence: 82%

Outcomes After Acute Myocardial Infarction in South Asian, Chinese, and White Patients

et al. 2010

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Background-Cardiac mortality rates vary substantially between countries and ethnic groups. It is unclear, however, whether South Asian, Chinese, and white populations have a variable prognosis after acute myocardial infarction (AMI).To clarify this association, we compared mortality, use of revascularization procedures, and risk of recurrent AMI and hospitalization for heart failure between these ethnic groups in a universal-access healthcare system. Methods and Results-We used a population cohort study design using hospital administrative data linked to cardiac procedure registries from British Columbia and the Calgary Health Region Area in Alberta (1994Alberta ( to 2003 to identify AMI cases. Patient ethnicity was categorized using validated surname algorithms. There were 2190 South Asian, 946 Chinese, and 38479 white patients with AMI identified. There was no significant difference in use of revascularization procedures between ethnic groups at 30 d and 1 year. Short-term (30-day) mortality was higher among Chinese relative to white patients (odds ratio, 1.23; 95% confidence interval, 1.02 to 1.48). There was no significant difference in 30-day mortality between South Asian and white patients. South Asian patients had a 35% lower relative risk of long-term mortality compared with white patients (hazard ratio, 0.65; 95% confidence interval, 0.57 to 0.72). There was no significant difference in long-term mortality between Chinese and white patients. Among AMI survivors, Chinese patients had a lower risk of recurrent AMI, whereas there was no difference between South Asian and white patients. Conclusion-The ethnic groups studied have striking differences in outcomes after AMI, with South Asian patients having significantly lower long-term mortality after AMI. (Circulation. 2010;122:1570-1577.)

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Section: Discussionsupporting

confidence: 82%

Outcomes After Acute Myocardial Infarction in South Asian, Chinese, and White Patients

et al. 2010

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“…For most sequelae, we made estimates on the basis of a database for all age-sex-country-year groups, with a Bayesian metaregression technique developed for the GBD 2010 (DisMod-MR). Several data sources have been used for the estimates of YLDs in China, including published studies, [33][34][35][36][37][38] multiple national surveys, 39,40 a set of 46 cancer registries, [41][42][43][44][45][46] Prevention (CDC) surveillance system. [47][48][49][50][51][52][53] The eff ects of treatment depending on the cause are captured through changes in prevalence, changes in the severity distribution across sequelae (eg, for chronic obstructive pulmonary disease), and for some injuries diff erent disability weights for treated and untreated outcomes.…”

Section: Ylds and Halementioning

confidence: 99%

Rapid health transition in China, 1990–2010: findings from the Global Burden of Disease Study 2010

et al. 2013

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“…In the present study, the in-hospital mortality rate was 15–15.4% in the HF group, in the mid-range of previously reported in-hospital mortality rates in western countries (21.6%) ( 22 ) and China (12.3%) ( 56 ). Certain hospital-based studies in China have reported short-term mortality rates following AMI ranging from 8.1–13.1% ( 41 , 57 ), which was higher compared with that in South Asian and Caucasian patients. This may be partly explained by a delayed presentation to emergency departments from the onset of AMI symptoms ( 58 ).…”

Section: Discussionmentioning

confidence: 92%

Influence of heart failure on the prognosis of patients with acute myocardial infarction in southwestern China

Deng¹,

Xia²,

Fu³

et al. 2016

Experimental and Therapeutic Medicine

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The impact of heart failure (HF) on acute myocardial infarction (AMI) in patients from southwestern China remains unclear. The present study aimed to compare in-hospital cardiovascular events, mortality and clinical therapies in AMI patients with or without HF in southwestern China. In total, 591 patients with AMI hospitalized between February 2009 and December 2012 were examined; those with a history of HF were excluded. The patients were divided into four groups according to AMI type (ST-elevated or non-ST-elevated AMI) and the presence of HF during hospitalization. Clinical characteristics, in-hospital cardiovascular events, mortality, coronary angiography and treatment were compared. Clinical therapies, specifically evidence-based drug use were analyzed in patients with HF during hospitalization, including angiotensin converting enzyme inhibitors (ACEIs) and β-blockers (BBs). AMI patients with HF had a higher frequency of co-morbidities, lower left ventricular ejection fraction, longer length of hospital stay and a greater risk of in-hospital mortality compared with AMI patients without HF. AMI patients with HF were less likely to be examined by cardiac angiography or treated with reperfusion therapy or recommended medications. AMI patients with HF co-treated with ACEIs and BBs had a significantly higher survival rate (94.4 vs. 67.5%; P<0.001) compared with untreated patients or patients treated with either ACEIs or BBs alone. Logistic regression analysis revealed that HF and cardiogenic shock in patients with AMI were the strongest predictors of in-hospital mortality. AMI patients with HF were at a higher risk of adverse outcomes. Cardiac angiography and timely standard recommended medications were associated with improved clinical outcomes.

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Comparison of Incidence, Mortality and Treatment of Acute Myocardial Infarction in Hospitals in Japan and China.

Abstract: Acute myocardial infarction (AMI) is one of the most intractable diseases and is increasing rapidly in Japan and China.

Cited by 6 publications

References 2 publications

Outcomes After Acute Myocardial Infarction in South Asian, Chinese, and White Patients

Outcomes After Acute Myocardial Infarction in South Asian, Chinese, and White Patients

Rapid health transition in China, 1990–2010: findings from the Global Burden of Disease Study 2010

Influence of heart failure on the prognosis of patients with acute myocardial infarction in southwestern China

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