Comparison of ivermectin and thiabendazole for treatment of naturally occurring nematode infections of goats in Kenya

Njanja, J C; Wescott, Richard B.; Ruvuna, F.

doi:10.1016/0304-4017(87)90006-9

Cited by 25 publications

(2 citation statements)

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“…Since the early reports on resistance of Haemonchus contortus to thiabendazole done in America by (7) and many more reports have emerged from other parts of the world including Kenya (8,9,10,11,12).…”

Section: Introductionmentioning

confidence: 99%

Prevalence of Gastrointestinal Nematodes Parasites From Sheep and Evaluation of Some Anthelminthic Resistance in Erbil Governorate

Ahmed¹,

Aziz²,

Abdullah³

2015

Bas.J.Vet.Res.

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Prevalence and anthelmintic resistance status of gastrointestinal nematodes in 430 sheep investigate by faecal examination was conducted in Qushtapa, Khabat, Benslawa, Salahaddin subdistricts in Erbil, from April to July 2012. The mean eggs per gram (EPG) count determined by using modified McMaster technique, showed that (40.46%) of the sheep were infested, the higher infection was 17.2% Nematodirus spp., 13.02% Strongylus spp., 4.18% Marshaligia spp., 2.79% Trichurus spp. and 3.25% with coccidia. Four farms were selected randomly each divided to control and three treatment groups: Levamisol, Albendazole and Ivermectin groups. Anthelmintic efficacy was measured after treatment dates were investigated with faecal egg count reduction test, the FECRT percentage for Levamisol in sheep ranged from 80.3 to 94.7 which show most effective in Khabat with FECRT of 94.7% while with Albendazole ranged from 75.5% to 80.2%, suspected resistant in all group, but the injectable Ivermectin in sheep ranged from 85.2 to 94.8 and show effective in Bnaslawa and Salahaddin with FECR of 94.6% and 94.8% respectively.All the anthelmintic were found to be low effective, but resistance to Albendazole was suspected. Based on the findings, it was concluded that development of anthelmintic resistance could be prevented by avoiding frequent dosing and under dosing, while strategic deworming should be practiced by both animal health workers and animal owners.

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Section: Introductionmentioning

confidence: 99%

Prevalence of Gastrointestinal Nematodes Parasites From Sheep and Evaluation of Some Anthelminthic Resistance in Erbil Governorate

Ahmed¹,

Aziz²,

Abdullah³

2015

Bas.J.Vet.Res.

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“…In Kenya several reports have indicated that some anthelmintic products have a lower than expected efficacy (Njanja and others 1987, Maingi 1991), possibly owing to the development of resistance by the target nematode parasites. However, during the course of a recent survey conducted by the National Veterinary Research Centre, Mguga (Wanyangu and others 1996) some anthelmintic products were found to be less effective than others containing the same active drug.…”

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confidence: 99%

Pharmaceutical quality of anthelmintics sold in Kenya

et al. 1998

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Nine anthelmintic products in pharmacies and from agricultural merchants in Kenya were tested for pharmaceutical quality. The concentration of active drug was compared with the claim on the label, and the variability of several products was tested between batches and between bottles within the same batch. All the products purchased claimed to contain levamisole but its mean (sd) concentration varied from 0 to 118.0 (13.3) per cent of the claimed. The concentration of levamisole in different batches of the same product ranged from 0 to 85.4 per cent of that claimed. One product consisting in part of mebendazole was found to contain 73.2 (9.4) per cent of the claimed concentration of this active component and two products consisting in part of oxyclozanide were found to contain 106.0 (14.4) and 120.6 (6.1) per cent of the expected concentration of oxyclozanide.

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Comparative efficacies of closantel, ivermectin, oxfendazole, thiophanate and levamisole against thiabendazole resistantHaemonchus contortus in sheep

Waruiru¹,

Weda²,

Otieno³

et al. 1996

Trop Anim Health Prod

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Comparison of ivermectin and thiabendazole for treatment of naturally occurring nematode infections of goats in Kenya

Cited by 25 publications

References 1 publication

Prevalence of Gastrointestinal Nematodes Parasites From Sheep and Evaluation of Some Anthelminthic Resistance in Erbil Governorate

Prevalence of Gastrointestinal Nematodes Parasites From Sheep and Evaluation of Some Anthelminthic Resistance in Erbil Governorate

Pharmaceutical quality of anthelmintics sold in Kenya

Comparative efficacies of closantel, ivermectin, oxfendazole, thiophanate and levamisole against thiabendazole resistantHaemonchus contortus in sheep

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