Comparison of Ketamine-Xylazine, Butorphanol-Azaperone-Medetomidine, and Nalbuphine-Medetomidine-Azaperone for Raccoon (Procyon Lotor) Immobilization

Johnson, Shylo R.; Ellis, Christine K.; Wickham, Chad K.; Selleck, Molly R.; Gilbert, Amy T.

doi:10.7589/jwd-d-23-00060

Cited by 1 publication

(1 citation statement)

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“…The average induction time for rhinos decreased from 8.9 min for etorphine alone to 6.3 min with the addition of azaperone. No changes in physiological parameters during the recovery period, including arterial blood gas analysis, were observed (Buss et al, 2022;Johnson et al, 2023;Sheldon, 2023;Somers, 2023). Thus, azaperone has a calming influence on animals due to its effect on serotonin receptors.…”

Section: The Use Of Azaperone For the Correction Of Behavioral Disord...mentioning

confidence: 97%

The use of anxiolytic drugs for the correction of behavioral disorders in mammals

Poroshinska,

Polishchuk,

Shmayun

et al. 2024

Regul. Mech. Biosyst.

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The issue of stress and behavioral disorders are growing significantly in the contemporary word in humans and animals alike. Various drugs are used to modify affected behavior, including psychotropic, anticonvulsant, antihistamines, hormones, analgesics, and neuroleptics. Psychotropic drugs are prescribed for animals with behavioral disorders, signs of anxiety or hypersensitivity. Improving the methods of diagnosing and treating behavioral disorders in animals can enhance animal welfare and optimize animal husbandry technology. Future research should be aimed at improving and optimizing the use of psychotropic drugs for behavioral disorders of various animal species. The main indication for the use of anxiolytic drugs is behavioral disorders associated with anxiety in wild and domestic animals. When anxiolytic drugs are used in mammals their pharmacological properties, the dependence of their action on the route of administration, age and species of the animal, and the ability to selectively affect the central nervous system should be taken into account. The most commonly used drugs for the treatment of behavioral disorders in animals are fluoxetine, amitriptyline, escitalopram, haloperidol, zuclopentixol and azaperone. Fluoxetine is an effective drug for the treatment of dogs with behavioral disorders associated with psychological changes. An important component of escitalopram's pharmacological effect is the psychomotor influence, when the animal's behavior changes are due to improved motor activity. Zuclopentixol has a wide range of anxiolytic, sedative and analgesic effects when used in wild cloven-hoofed animals. Amitriptyline along with antidepressant properties, has a local analgesic impact. Azaperone has a pronounced anxiolytic and sedative effect on animals. It is widely used as an anti-stress agent to overcome anxiety caused by weaning, regrouping or veterinary manipulations. Azaperone is often used to control aggressive behavior in group housing, especially in the pig industry. The psychotropic drugs surveyed in this paper, along with direct anxiolytic action, are able to manifest additional physiological effects, which should be taken into account when developing treatment protocols for animals with behavioral problems. Further targeted studies are required to assess the pharmacological effects of anxiolytic drugs in animals.

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Section: The Use Of Azaperone For the Correction Of Behavioral Disord...mentioning

confidence: 97%

The use of anxiolytic drugs for the correction of behavioral disorders in mammals

Poroshinska,

Polishchuk,

Shmayun

et al. 2024

Regul. Mech. Biosyst.

View full text Add to dashboard Cite

show abstract

Comparison of Ketamine-Xylazine, Butorphanol-Azaperone-Medetomidine, and Nalbuphine-Medetomidine-Azaperone for Raccoon (Procyon Lotor) Immobilization

Abstract: BioOne Complete (complete.BioOne.org) is a full-text database of 200 subscribed and open-access titles in the biological, ecological, and environmental sciences published by nonprofit societies, associations, museums, institutions, and presses.

Cited by 1 publication

References 28 publications

The use of anxiolytic drugs for the correction of behavioral disorders in mammals

The use of anxiolytic drugs for the correction of behavioral disorders in mammals

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