Comparison of laminar and plug flow-fields on extraction performance in micro-channels

Malengier, Benny; Tamalapakula, JL; Pushpavanam, S.

doi:10.1016/j.ces.2012.03.027

Cited by 15 publications

(16 citation statements)

References 16 publications

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“…Microreactors represent an attractive tool for accelerating mass transfer 25,26 and kinetics measurements, 27‐29 owing to their excellent mixing performance, improved process control, and inherent safety. Continuous flow microreactors for biocatalytic reactions have attracted attention in recent years because of their high production efficiency, controllability, and environmental sustainability 30‐32 .…”

Section: Introductionmentioning

confidence: 99%

Experimental and model‐based study of biohydration of acrylonitrile to acrylamide in a microstructured chemical system

et al. 2020

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Experimental and model‐based studies of acrylonitrile biohydration catalyzed by free cells were conducted in this work. The high ratios of the two phases of the reaction system and the effects of inhibition and inactivation on the enzyme make the process complicated; thus, its exact kinetics have never been reported. To fully understand and model the reaction, a microstructured chemical system was employed to investigate droplet dispersion, the mass transfer process, the intrinsic kinetics with inhibition and inactivation, and the preparation process of acrylamide. By adjusting the structure size and flow conditions of the microreactor, acrylonitrile droplets of 40 μm were obtained and enhanced mass transfer was achieved. Compared to previous studies, the microchemical system in our work provides more accurate kinetic parameters, with a much higher maximum reaction rate and much smaller Michaelis constant. The numerical predictions of the process model show good agreement with experimental results.

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Section: Introductionmentioning

confidence: 99%

Experimental and model‐based study of biohydration of acrylonitrile to acrylamide in a microstructured chemical system

et al. 2020

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“…This model can also be applied to extraction in electro-osmotic flow, wherein the transverse velocity profile is spatially uniform [3,4]. The effect of the velocity profile on extraction performance has been studied for different system parameters by Malengier et al [15].…”

Section: D Plug Model: Plug Flow Between Infinite Flat Platesmentioning

confidence: 97%

“…If the flow is driven by a pressure gradient, then the appropriate plug velocities are the average velocities of the two phases, as calculated by integrating Equations (15) and (16). This model can also be applied to extraction in electro-osmotic flow, wherein the transverse velocity profile is spatially uniform [3,4].…”

Section: D Plug Model: Plug Flow Between Infinite Flat Platesmentioning

confidence: 98%

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Modelling Extraction in Microchannels with Stratified Flow: Channel Geometry, Flow Configuration and Marangoni Stresses

Picardo

Radhakrishna

Vir

et al. 2015

Indian Chemical Engineer

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In this work, we present a hierarchy of mathematical models for extraction in microchannels with two-phase stratified flow. A flat stable inter-fluid interface is considered. We present three models for rectangular channels, of varying degrees of complexity: 2D, 1D Laminar and 1D Plug models. The predictions of these models are compared with each other and with experiments reported in the literature. Conditions under which a simpler 1D model can replace the complex 2D model are identified. Next, a detailed model for channels with a circular cross-section is developed using bipolar cylindrical coordinates. We also show how a much simpler description can be obtained by applying the 1D rectangular channel models to a circular channel. The relative performance of co-current and countercurrent flow configurations is analysed next, using the 1D Plug flow model. Finally, the model is extended to account for Marangoni stresses that result from the variation of interfacial tension with solute concentration. The effect of Marangoni stresses on extraction in stable stratified flow is found to be insignificant. This is because the flow induced by Marangoni stresses is too weak to control the pressure-driven primary flow.

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“…al., 2012). Microreactors favor the reaction of the immiscible reagents in the transesterification, since the molecular diffusive effects occur more rapidly due to the significant reduction in the diffusion path length (Malengier et. al., 2012), resulting in more effective mass and heat transfer processes.…”

Section: -Introductionmentioning

confidence: 99%

Approximation error model (AEM) approach with hybrid methods in the forward-inverse analysis of the transesterification reaction in 3D-microreactors

Pontes

Costa

Naveira-Cotta

et al. 2021

Inverse Problems in Science and Engineering

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Approximation error model (AEM) approach with hybrid methods in the forwardinverse analysis of the transesterification reaction in 3D-microreactorsThis work advances the approximation error model approach for the inverse analysis of the biodiesel synthesis using soybean oil and methanol in 3Dmicroreactors. Two hybrid numerical-analytical approaches of reduced computational cost are considered to offer an approximate forward problem solution for a three-dimensional nonlinear coupled diffusive-convective-reactive model. First, the Generalized Integral Transform Technique (GITT) is applied using approximate non-converged solutions of the 3D model, by adopting low truncation orders in the eigenfunction expansions. Second, the Coupled Integral Equations Approach (CIEA) provides a reduced mathematical model for the average concentrations, which leads to inherently approximate solutions. The AEM approach through the Bayesian framework is illustrated in the simultaneous estimation of kinetic and diffusion coefficients of the transesterification reaction.For this purpose, the fully converged GITT results with higher truncation orders for the 3D partial differential model are employed as reference results to define the approximations errors. The results highlight that either the non-converged solutions via GITT or the reduced model solution obtained via CIEA, when taking into account the model error, are robust and cost-effective alternatives for the inverse analysis of nonlinear convection-diffusion-reaction problems.

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Comparison of laminar and plug flow-fields on extraction performance in micro-channels

Cited by 15 publications

References 16 publications

Experimental and model‐based study of biohydration of acrylonitrile to acrylamide in a microstructured chemical system

Experimental and model‐based study of biohydration of acrylonitrile to acrylamide in a microstructured chemical system

Modelling Extraction in Microchannels with Stratified Flow: Channel Geometry, Flow Configuration and Marangoni Stresses

Approximation error model (AEM) approach with hybrid methods in the forward-inverse analysis of the transesterification reaction in 3D-microreactors

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