Comparison of laser epithelial keratomileusis and photorefractive keratectomy for low to moderate myopia

Lee, Jae Bum; Seong, Gong Je; Lee, Jong Hyuck; Seo, Kyoung Yul; Lee, Young Ghee; Kim, Eung Kweon

doi:10.1016/s0886-3350(00)00880-4

Cited by 207 publications

(148 citation statements)

References 22 publications

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“…In contrast, in epi-LASIK, the epikeratome creates a perfectly round, smooth-edged epithelial flap without any irregularities in Bowman’s membrane, and this clean, regular flap border could promote rapid healing across the cornea [11,13,15,16,25]. During the scraping procedure in PRK, the basement membrane is broken, and proinflammatory cytokines are released and directly affect stromal keratocytes [3,24].…”

Section: Discussionmentioning

confidence: 99%

“…Epithelial flaps in epi-LASIK differ from those in LASEK in that the epikeratome can precisely cleave the epithelium underneath the basement membrane without the need for alcohol [10,11,12,13,14]. Theoretically, epithelial flaps should be associated with less postoperative pain, faster visual recovery, and less corneal haze [15,16] and should control corneal wound healing, by acting as a mechanical barrier between the tear film and ablated stroma [11]. The opposite results have recently been reported: postoperative epithelial damage such as reduction of the basal cells leads to a delay in visual recovery and increase in pain [17,18].…”

Section: Introductionmentioning

confidence: 99%

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Effect of Flap Removal in Myopic Epi-LASIK Surgery on Visual Rehabilitation and Postoperative Pain: A Prospective Intraindividual Study

Lee

Park

et al. 2010

Ophthalmologica

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Purpose: A prospective intraindividual study to evaluate the effect of flap removal in myopic epi-LASIK surgery on visual rehabilitation and postoperative pain. Methods: Ninety eyes of 45 patients were treated for myopia with epi-LASIK. In each patient, the epithelial flap was repositioned in one eye after epi-LASIK (group 1) while the flap was removed in the other (group 2). Uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA), spherical equivalent (SE) refraction, postoperative pain and corneal haze were examined for 6 months after surgery in both groups. Results: Group 2 had a better UCVA at 4 days and BCVA at 1 week after surgery (p = 0.001, p = 0.043) than group 1. No significant differences were observed between the two groups in terms of UCVA, BCVA, or SE refraction at 1 week and 1, 2 and 6 months. Postoperative pain scores were similar for both groups. In group 2, severe pain (pain level ≧6) was relatively less than in group 1 at 2 h and 12 h after surgery. Corneal haze levels in both groups were not different. Conclusions: Epi-LASIK surgery with flap removal was found to significantly promote re-epithelialization and visual recovery during the early postoperative period. It was also found to be more predictable and less painful than epi-LASIK surgery.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Effect of Flap Removal in Myopic Epi-LASIK Surgery on Visual Rehabilitation and Postoperative Pain: A Prospective Intraindividual Study

Lee

Park

et al. 2010

Ophthalmologica

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“…All patients underwent operation by a single surgeon with Technolas laser machine (Technolas 217z100, Bausch & Lomb, Rochester, NY, USA). The residual epithelial defect size was measured in both eyes after 4 days from surgery because most of previous studies noted approximately 4 days as mean average time to complete healing [13][14][15]. After primary preparations, and instillation of topical proparacaine 0.5%, the eyes were exposed using a wire lid speculum and epithelium was removed manually in a centripetal fashion using a Weck-Cel sponge spatula on RE and blunt hockey blade on LE.…”

Section: Methodsmentioning

confidence: 99%

Epithelial Defect Induced Photorefractive Surgery: Comparison of Two Mechanical Epithelial Removal Techniques

Alishiri¹

2013

CMR

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Abstract:Purpose: To compare the epithelial defect size after epithelial removal by Weck-Cel sponge (Medtronic) spatula and blunt scalpel hockey blade. Method: This prospective study comprised 100 cases of PRK with mean age of 26±5 years (range, 19 to 45) performed at Bina Eye Specialist Hospital from January to march 2012. The size of epithelium removal was the same in all patients and it was 8.5 mm 2 . Each patienst's right eyes epithelium was removed by Weck spounge and it was removed by Haki spatula in the left eye. The residual epithelial defect size was measured in both eyes after 4 days from surgery. Result: Of 200 eyes that met the inclusion criteria, the mean preoperative spherical equivalent (SE) refractive error in right eyes was -2.6±1.5 (Range: -1 to -7 D) versus 2.6±1.4 (Range: -1 to -6.5D) in left eyes (P= 0.527 ). The mean epithelial defect size after 4 days in right eyes was 1.5+-0.77 and it was 1.46 +-0.77 in the left eyes (P = 0.623). Conclusion: This sudy showed that there is no difference between corneal epithelial defect size in two methods of PRK surgery after corneal epithelial removal .We consider both methods to be comparable in terms of efficacy and believe the choice of one method over the other rests on the surgeon's decision and experience.

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“…1: Anzahl der Fehlsichtigkeiten in Deutschland -Angabe in Mio. Menschen [11] Die Nachfrage nach Excimer-Laserchirurgie zur Korrektur von Fehlsichtigkeit ist in den letzten Jahren stark angestiegen [77,37]. Allein im Jahre 2007 haben sich in Deutschland etwa 100 000 Menschen für eine LASIK-Laseroperation entschieden.…”

Section: Einleitung: Zielsetzung Der Vorliegenden Arbeitunclassified

Sozioökonomischer Vergleich zwischen laserrefraktivbehandelten und unbehandelten Patienten in Mittelhessen

Sekundo¹,

Rebhan²,

Scherag³

2008

Klin Monatsbl Augenheilkd

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Comparison of laser epithelial keratomileusis and photorefractive keratectomy for low to moderate myopia

Abstract: Laser epithelial keratomileusis safely and effectively treated eyes with low to moderate myopia. It reduced the incidence of significant postoperative pain and corneal haze and may prevent the flap- and interface-related problems of laser in situ keratomileusis.

Cited by 207 publications

References 22 publications

Effect of Flap Removal in Myopic Epi-LASIK Surgery on Visual Rehabilitation and Postoperative Pain: A Prospective Intraindividual Study

Effect of Flap Removal in Myopic Epi-LASIK Surgery on Visual Rehabilitation and Postoperative Pain: A Prospective Intraindividual Study

Epithelial Defect Induced Photorefractive Surgery: Comparison of Two Mechanical Epithelial Removal Techniques

Sozioökonomischer Vergleich zwischen laserrefraktivbehandelten und unbehandelten Patienten in Mittelhessen

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