Comparison of lipid profile in tobacco and non-tobacco abusers – A comparative study

Abstract

To evaluate and correlate the salivary and serum lipid profile in healthy individuals, tobacco chewers and smokers. Also, to compare the salivary lipid profile within each group statistically. Materials and Methods: A total of 60 samples were taken, 20 in each group. Fasting blood and unstimulated saliva sample collected and the lipid analysis (Total Cholesterol-TCHL, Triglycerides-TGL, High density lipid cholesterol-HDL, Low density lipid cholesterol-LDL, very low-density lipid cholesterol-VLDL) were done on an autoanalyzer based on spectrophotometric principle. Statistical analysis: Data was evaluated and statistical analysis was done using unpaired student "t" test and Karl Pearson's correlation. Results: A moderate correlation was found between salivary and serum lipid profile of the study group and control group with exception to LDL. Low lipid profile was observed in the study group in comparison with control group. Conclusion: Saliva can be used as a non-invasive diagnostic tool for assessing lipid profile, however diagnostic value of saliva has to be determined in terms of sensitivity, specificity and reproducibility in larger samples and different disease setting.