Comparison of long-term results between laparoscopy-assisted gastrectomy and open gastrectomy with D2 lymph node dissection for advanced gastric cancer

Hamabe, Atsushi; Omori, Takeshi; Nishida, Toshirou

doi:10.1007/s00464-011-2096-0

Cited by 91 publications

(62 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A small number of investigators reported that laparoscopic gastrectomy was oncologically a safe procedure for AGC with long-term outcomes similar to those for open surgery [29,30]. This study also showed that the laparoscopic procedure did not increase peritoneal recurrence.…”

Section: Discussionmentioning

confidence: 51%

Factors predicting peritoneal recurrence in advanced gastric cancer: implication for adjuvant intraperitoneal chemotherapy

et al. 2013

View full text Add to dashboard Cite

Background Despite adjuvant chemotherapy, patients with advanced gastric cancer (AGC) often develop recurrence, and the peritoneum is the most common site of recurrence. Therefore, intraperitoneal chemotherapy (IPC) has been proposed as a treatment option. The aim of this study was to select the eligible patients for application of IPC. The first site of recurrence was the peritoneum in 144 patients (58.8 %), and the 5-year peritoneal recurrence-free survival was 79.3 %. Depth of tumor invasion CT3, extensive lymph node metastasis (N3), Bormann type 4, infiltrative type (Ming's classification), and venous invasion were independent risk factors for peritoneal recurrence. In subgroup analysis with patients who had received adjuvant chemotherapy (n = 481), depth of tumor invasion CT3, Bormann type 4, infiltrative type (Ming's classification), and venous invasion were independent risk factors for peritoneal recurrence. When a peritoneal recurrence risk index was made with each risk factor assigned 1 point (2 points for T4 stage), peritoneal recurrence rates with 0, 1, 2, 3, 4, or 5 points were 0 %, 3.9 %, 13.1 %, 33.3 %, 44.0 %, and 72.0 %, respectively, in those patients. Conclusions Patients at higher risk for peritoneal recurrence can be identified from the findings of this study. Further prospective studies are required to evaluate the usefulness of IPC for these patients.

show abstract

Section: Discussionmentioning

confidence: 51%

Factors predicting peritoneal recurrence in advanced gastric cancer: implication for adjuvant intraperitoneal chemotherapy

et al. 2013

View full text Add to dashboard Cite

show abstract

“…Some authors have reported that LADG also has short-term benefits and oncological safety for advanced gastric cancer [2]. The technical feasibility and oncological safety of LTG have also been recently reported.…”

Section: Discussionmentioning

confidence: 97%

“…Currently, because LADG is considered technically feasible and oncologically safe for the treatment of early gastric cancer, its indications have been extended from early gastric cancer to advanced disease [2]. Because the indication for LADG has expanded, surgeons who have experience with LADG cautiously attempt laparoscopic total gastrectomy (LTG) in selected patients [3].…”

Section: Introductionmentioning

confidence: 99%

The learning curve associated with laparoscopic total gastrectomy

et al. 2014

View full text Add to dashboard Cite

Background Although the frequency of laparoscopic total gastrectomy (LTG) has been increasing, the procedure requires considerable experience because of its technical difficulty and the concern for oncological safety. This study intended to define the learning curve associated with the procedure. Methods All 256 cases of LTG performed from June 2003 to December 2012 were enrolled. The cases were divided into ten groups of 25 cases based on when they occurred. The learning curve was defined using the moving average method. LTG, performed in the absence of other procedures (pure-LTG, 132 cases), was extracted from the ten groups, and the mean operative time and estimated blood loss (EBL) were compared to define the learning curve. Retrieved lymph nodes, hospital stay, and complications were compared across the phases of the learning curve. LTG with spleen resection, performed in the absence of other procedures (pure-srLTG, 53 cases), was also analyzed by the same method. Results A three-phase learning curve of LTG was defined: the first two groups, the following two groups, and the final six groups (mean operative time: 223.0, 244.8, and 207.8 min, respectively, p = 0.003; mean EBL: 94.6, 237.0, and 116.5 ml, respectively, p \ 0.001). The rates of complications and open conversions were similar across the three phases. There were no significant differences in mean operative time, EBL, retrieved LNs, hospital stay, or complication rates between pure-LTG and pure-srLTG, after completing the respective learning curves. Conclusions Experience with approximately 100 LTG cases was required to complete learning of the procedure.

show abstract

“…There were no significant differences in hospital mortality. DFS in LTG was similar to that in OTG (HR, 0.62; 95% CI, 0.30, 1.27; P= 0.191) (Fig.2-3) [1][2][3][12][13][14][15][16][17][18][19][20].…”

Section: Discussionmentioning

confidence: 71%

Laparoscopic Subtotal/Total Gastrectomy (LS/TG) Versus Open Subtotal/Total Gastrectomy (OS/TG) For Gastric Cancer: Literature Review to Activate the Laparoscopic Procedure Gastric Cancer Resection in Secondary Care Hospital

Coco¹

2017

MOJCR

View full text Add to dashboard Cite

Comparison of long-term results between laparoscopy-assisted gastrectomy and open gastrectomy with D2 lymph node dissection for advanced gastric cancer

Abstract: The findings show that LAG with D2 lymph node dissection is acceptable in terms of long-term results for advanced gastric cancer cases and may be applicable for advanced gastric cancer treatment.

Cited by 91 publications

References 33 publications

Factors predicting peritoneal recurrence in advanced gastric cancer: implication for adjuvant intraperitoneal chemotherapy

Factors predicting peritoneal recurrence in advanced gastric cancer: implication for adjuvant intraperitoneal chemotherapy

The learning curve associated with laparoscopic total gastrectomy

Laparoscopic Subtotal/Total Gastrectomy (LS/TG) Versus Open Subtotal/Total Gastrectomy (OS/TG) For Gastric Cancer: Literature Review to Activate the Laparoscopic Procedure Gastric Cancer Resection in Secondary Care Hospital

Contact Info

Product

Resources

About