Comparison of long-term survival of total abdominal radical hysterectomy and laparoscopy-assisted radical vaginal hysterectomy in patients with early cervical cancer: Korean multicenter, retrospective analysis

Abstract

Comparison of long-term survival between total TARH and LARVH was investigated in patients with early cervical cancer. • The 5-year PFS and OS rates did not differ statistically between TARH and LARVH. • The non-inferiority of LARVH to TARH in 5-year PFS and OS rates was confirmed.

Adjuvant Radiotherapy After Minimally Invasive Surgery in Patients With Stage IA1-IIA1 Cervical Cancer

“…These two studies compared the recurrence and survival results of patients with early cervical cancer undergoing open surgery and minimally invasive surgery, and found that the survival of patients in the open surgery group was significantly better than that of the minimally invasive surgery group, which completely contrary to previous results ( 10 – 16 ). The same results were obtained in subsequent studies by other institutions ( 17 , 18 ). It caused great shock and controversy in the international community.…”

Value of Radiotherapy After Minimally Invasive Surgery in Patients With Stage IA1-IIA1 cervical cancer

“…These two studies compared the recurrence and survival results of patients with early cervical cancer undergoing open surgery and minimally invasive surgery, and found that the survival of patients in the open surgery group was signi cantly better than that of the minimally invasive surgery group, which completely contrary to previous results [8][9][10][11][12][13][14][15] . The same results were obtained in subsequent studies by other institutions 16,17 . It caused great shock and controversy in the international community.…”

Laparo-assisted vaginal radical hysterectomy as a safe option for minimal invasive surgery in early stage cervical cancer: A systematic review and meta-analysis

“…Except for Li [16], Park [17] and Kwon [26], all the other studies avoided the use of uterine manipulators. Moreover, Kanno [14], and Fugesi [24] explixity declared that they systematically removed surgical specimens into a collection bag.…”

“…Köhler et al [15] proposed the largest series with 389 patients undergone to LARVH and the longest mean FUP of 99 months (3 years DFS 96.8%; 3 years OS 98.5%; 4.5 years DFS 95.7%; 4.5 years DFS 97.6%). Kwon et al [26], vice versa, reported the largest comparative study, with the arm of LARVH composed of 252 patients, which presented a 5 years DFS and OS of 86.6% and 88% during a mean of 82 months FUP. Li et al [16] is the latest article published, with 137 patients and 53 months of FUP, showing a 5 years DFS of 96.4% and 5 years OS of 96.8%.…”