Comparison of low-strength compression stockings with bandages for the treatment of recalcitrant venous ulcers

Brizzio, E. O.; Amsler, Felix; Lun, Bertrand; Blättler, W.

doi:10.1016/j.jvs.2009.08.048

Cited by 66 publications

(55 citation statements)

References 16 publications

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“…23,27 Numerous studies have proven the effect of compression therapy on venous and lymphatic system, 1,19,31 whether compression is performed with bandages or stockings. 5 The efficacy of the treatment mainly depends on the level of pressure which is applied on the limb. 14,24 This level of pressure depends on several parameters such as: -Other parameters such as friction between the different layers, mechanical properties of the limb soft tissues,……”

Section: Introductionmentioning

confidence: 99%

Experimental Investigation of Pressure Applied on the Lower Leg by Elastic Compression Bandage

Chassagne

Martin²,

Badel³

et al. 2015

Ann Biomed Eng

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Compression therapy with stockings or bandages is the most common treatment for venous or lymphatic disorders. The objective of this study was to investigate the influence of bandage mechanical properties, application technique and subject morphology on the interface pressure, which is the key of this treatment. Bandage stretch and interface pressure measurements (between the bandage and the leg) were performed on 30 healthy subjects (15 men and 15 women) at two different heights on the lower leg and in two positions (supine and standing). Two bandages were applied with two application techniques by a single operator. The statistical analysis of the results revealed: no significant difference in pressure between men and women, except for the pressure variation between supine and standing positions; a very strong correlation between pressure and bandage mechanical properties (p < 0.00001) and between pressure and bandage overlapping (p < 0.00001); a significant pressure increase from supine to standing positions (p < 0.0001). Also, it showed that pressure tended to decrease when leg circumference increased. Overall, pressure applied by elastic compression bandages varies with subject morphology, bandage mechanical properties and application technique. A better knowledge of the impact of these parameters on the applied pressure may lead to a more effective treatment.

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Section: Introductionmentioning

confidence: 99%

Experimental Investigation of Pressure Applied on the Lower Leg by Elastic Compression Bandage

Chassagne

Martin²,

Badel³

et al. 2015

Ann Biomed Eng

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“…Healing within 90 days was observed in 36% of patients using MCS and in 48% using four layers compression bandages (P = 0.35). Healing within 180 days was documented in 50% of MCS patients and in 67% with four layers compression bandages (P = 0.21) [12].…”

Section: Discussionmentioning

confidence: 97%

Low-Level Laser Therapy versus Four Layers Compression Technique in the Treatment of Venous Ulcers

El-Laboudy¹,

Samir²,

Tawfik³

et al. 2014

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Objective: The aim of the study is to evaluate the effect of low-level laser therapy in comparison to compression bandage therapy in the treatment of venous ulcers. Subjects & Methods: This study was carried out in the period from March 2013 to March 2014. The study included 40 adult patients with a diagnosis of venous ulcer classified as C6 according to the clinical classification of CEAP classification. The patients were divided into 2 groups: the first one included 20 patients treated by low-level laser therapy at the Rheumatology and Rehabilitation department, and the second group included 20 patients in whom we use four layers compression bandaging at the vascular surgery department. Results: 32 ulcers were treated in group I and 35 ulcers were treated in group II. The patients of group I were 7 (35%) females and 13 (65%) males, their age range were (24 -56) years. The patients of group II were 11 (55%) males and 9 (45%) females; their age ranges were (32 -50) years. Measurements of the ulcers size by (cm 2 ) were taken at the beginning of therapy, at 1 month, at 2 months and at 3 months later on. The calculation of the area of the ulcer was done by using the graph papers to document the ulcer's perpendicular linear dimensions. According to the size of the ulcer, some ulcers heal within 1 month (15.6%) ulcers in group I, and (28.5%) in group II. Some ulcers heal within 2 months (28%) in group I, and (37%) in group II. The remaining ulcers heal within 3 months or more which are (56%) ulcers in group I, and (34.2%) ulcers in group II. The recurrence rate of chronic venous leg ulcer in compression bandage technique used in group II was the least one as the total number of recurrent cases were 5 (25%), followed by laser therapy used in group I. Conclusion: There was no significant efficacy of the low-level laser therapy over the four layers compression technique in the management of chronic venous ulcers.

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“…It is important to emphasize that the patients belonged to the group of refractory cases included in the previous study already mentioned. 16 This assay showed that 50% of ulcers showed complete closure using medical compression stockings, and 67% of complete closure with multilayer bandages, after 180 days.…”

Section: Discussionmentioning

confidence: 99%

“…Nine patients were selected from a cohort of 55 patients who had previously completed the aforementioned comparative study of lowstrength medical compression stockings with bandages for treating recalcitrant venous ulcers, 16 after a long period without showing any improvement in the ulcers' features (e.g. dimensions, color intensity of dyschromia), as well as pain and CIVIQ.…”

Section: Patientsmentioning

confidence: 99%

“…Five studies revealed an advantage in the use of stockings over bandages, while three other assays showed no difference. 15 Our aim was to study the effect of liposomated bovine Lactoferrin, locally applied on the surface of UHD, in 9 patients with long-lasting evolution of refractory CVI, selected from our previous study, 16 and to evaluate its potential relation to the iron metabolism profile and mutations of HH genes. 17 …”

Section: Introductionmentioning

confidence: 99%

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Ulcerated hemosiderinic dyschromia and iron deposits within lower limbs treated with a topical application of biological chelator

Brizzio¹,

Castro

Narbaitz

et al. 2012

Veins and Lymphatics

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The ulcerative haemosiderinic dyschromia of chronic venous insufficiency is difficult to heal and presents a high accumulation of iron. Lactoferrin, a potent natural iron chelator, could help to scar this ulcerative haemosiderinic dyschromia. The objective of this study was to determine whether the topical application of a liposomal gel with Lactoferrin favors scarring/degradation of the brown colored spot typical of ulcerative haemosiderinic dyschromia. Nine patients with severe chronic venous insufficiency and ulcerative haemosiderinic dyschromia (CEAP-C6), with a natural evolution of over 12 months, were included in the study. Hemo chromatosis gene mutations were investigated. The levels of serum ferritin, transferrin saturation and blood cell counts were analyzed. The presence of hemosiderin was investigated through periulcerous and ulcer fundus biopsies carried out at baseline and 30 days after treatment with Lactoferrin. The severity of the injuries (CEAP classification) was evaluated at the beginning of and throughout the whole 3-month treatment period. No patient had received compression treatment during the three months previous to this therapy. Significant improvement in these injuries, with a reduction in the dimensions of the brown spot (9 of 9) at Day 90, and complete scarring with a closure time ranging from 15 to 180 days (7 of 9) were observed. The use of topical lactoferrin is a non-invasive therapeutic tool that favors clearance of hemosiderinic dyschromia and scarring of the ulcer. The success of this study was not influenced either by the hemochromatosis genetics or the iron metabolism profile observed.

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Comparison of low-strength compression stockings with bandages for the treatment of recalcitrant venous ulcers

Cited by 66 publications

References 16 publications

Experimental Investigation of Pressure Applied on the Lower Leg by Elastic Compression Bandage

Experimental Investigation of Pressure Applied on the Lower Leg by Elastic Compression Bandage

Low-Level Laser Therapy versus Four Layers Compression Technique in the Treatment of Venous Ulcers

Ulcerated hemosiderinic dyschromia and iron deposits within lower limbs treated with a topical application of biological chelator

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