2020
DOI: 10.1097/md.0000000000020932
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Comparison of magnetic resonance imaging and 18-fludeoxyglucose positron emission tomography/computed tomography in the diagnostic accuracy of staging in patients with cholangiocarcinoma

Abstract: Background: Accurate clinical staging of patients with cholangiocarcinoma (CCA) has a significant impact on treatment decisions. In this study, we aimed to compare the diagnostic value of magnetic resonance imaging (MRI) and 18-fludeoxyglucose positron emission tomography/computed tomography ( 18 F-FDG PET/CT) for staging of CCA. Methods: We performed comprehensive systematic search in Web of Science (including MEDLINE) and Excerpta Medica Dat… Show more

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Cited by 22 publications
(21 citation statements)
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“…At present, there is still a lack of unified guidelines for the assessment of benign and malignant parotid tumors before surgery. Most clinicians can diagnose them solely on personal clinical experience (18). This is more subjective and uncertain in empirical medicine, which may cause misdiagnosis and affect the treatment and prognosis of patients.…”
Section: Preoperative Diagnosis Of Benign and Malignant Parotidmentioning
confidence: 99%
“…At present, there is still a lack of unified guidelines for the assessment of benign and malignant parotid tumors before surgery. Most clinicians can diagnose them solely on personal clinical experience (18). This is more subjective and uncertain in empirical medicine, which may cause misdiagnosis and affect the treatment and prognosis of patients.…”
Section: Preoperative Diagnosis Of Benign and Malignant Parotidmentioning
confidence: 99%
“…A recent meta-analysis, comparing 18 F-FDG PET/CT and MR in staging iCCA, found no significant difference in primary tumor detection, though PET offered improved detection of nodal metastatic disease. 20 In addition to staging utility, 18 F-FDG PET/CT after radioembolization documents radioembolic distribution and, thus, tumor coverage (►Fig. 1).…”
Section: Imaging Featuresmentioning
confidence: 99%
“…However, data regarding regional node metastasis and N stage are limited owing to the unsatisfactory diagnostic accuracy of both imaging modalities. Furthermore, [ 18 F]FDG PET/CT has low sensitivity but high specificity for detecting distant metastasis, with reported pooled sensitivity and specificity of 56% and 95%, respectively [ 8 ]. Gallium (Ga)68-labelled fibroblast activating protein inhibitor (FAPI) was developed to evaluate fibroblast activation in oncological imaging, with fibroblast activating proteins being highly expressed in cancer-associated fibroblasts in various epithelial carcinomas.…”
Section: Introductionmentioning
confidence: 99%