Comparison of magnetic resonance real-time imaging of left ventricular function with conventional magnetic resonance imaging and echocardiography

Schalla, Simon; Nagel, Eike; Lehmkuhl, H.; Klein, Christoph; Bornstedt, Axel; Schnackenburg, Bernhard; Schneider, Uta; Fleck, Eckart

doi:10.1016/s0002-9149(00)01279-0

Cited by 104 publications

(79 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Real-time cine frames can also be acquired during free breathing and without ECG-gating. This is a major advantage enabling cardiac MR imaging examinations in patients with arrhythmia or in patients who are unable to hold their breath (23,27,28). The time savings of the real-time technique are tremendous as only one breath-hold period is needed to cover the entire LV compared to about 12 minutes with the conventional single-slice approach (29).…”

Section: Discussionmentioning

confidence: 99%

“…The following criteria were used for contour tracing by an experienced observer: a rim of myocardium with complete LV wall thickness, i.e., without partial volume effects from the left atrium, had to be visible at 50% or more of the LV circumference in the most basal slice next to the mitral valve (7,13,(21)(22)(23). The LV outflow tract was included up to the level of the aortic valve (7,13).…”

Section: Image Analysismentioning

confidence: 99%

See 1 more Smart Citation

Assessment of left ventricular function by breath‐hold cine MR imaging: Comparison of different steady‐state free precession sequences

Kunz

Oellig

Krummenauer

et al. 2005

Magnetic Resonance Imaging

View full text Add to dashboard Cite

Purpose:To compare steady-state free precession (SSFP) sequence protocols with different acquisition times (TA) and temporal resolutions (tRes) due to the implementation of a view sharing technique called shared phases for the assessment of left ventricular (LV) function by breath-hold cine magnetic resonance (MR) imaging. Materials and Methods:End-diastolic and end-systolic volumes (EDV, ESV) were measured in contiguous shortaxis slices with a thickness of 8 mm acquired in 10 healthy male volunteers. The following true fast imaging with steady-state precession (TrueFISP) sequence protocols were compared: protocol A) internal standard of reference, segmented: tRes 34.5 msec, TA 18 beats per slice; protocol B) segmented, shared phases: tRes 34.1 msec, TA 10 beats per slice; and protocol C) real-time, shared phases, parallel acquisition technique: tRes 47.3 msec, TA 24 beats for 12 slices covering the entire left ventricle. Results:Phase sharing leads to a significant decrease in EDV, stroke volume (SV), and ejection fraction (EF) (median difference -7.0 mL [*], -9.6 mL, and -3.4%, respectively, for protocol B; -15.3 mL, -13.3 mL, and -2.4% for protocol C; P ϭ 0.002, *P ϭ 0.021). The observed median difference of real-time EDV and SV estimates is of clinical relevance. Real-time cine MR imaging shows a greater variability of EDV and SV. No relevant differences in ESV were observed. Conclusion:The true cine frame duration of both shared phases sequence protocols exceeds the period of isovolumetric contraction (IVCT) of the left ventricle resulting in a systematic and significant underestimation of EDV and consequently SV and EF. SSFP sequence protocol parameters, particularly tRes and use of view sharing techniques, should therefore be known at follow-up examinations in order to be able to assess LV remodeling in patients with heart failure. CINE MAGNETIC RESONANCE (MR) imaging has beenshown to be the most accurate and reproducible method for the evaluation of cardiac ventricular volumes, function, and mass and is therefore regarded to be the standard of reference (1-4). Two different MR sequences are commonly used to assess cardiac function parameters non-invasively: segmented k-space turbo gradient echo (TGE) and steady-state free precession (SSFP) sequences.The accuracy of segmented k-space TGE sequences has been extensively evaluated, including animal experiments (5-8). The recently introduced SSFP sequences enable shorter acquisition times, allow higher in-plane resolutions, and provide better image quality (8,9). Their accuracy in determining left ventricular (LV) mass was also evaluated in animal experiments (10). Normal values were established for left and right ventricular volumes and function for both TGE as well as SSFP sequences, with SSFP sequences yielding significantly larger end-diastolic and end-systolic volumes (EDV and ESV, respectively) than TGE sequences (7,8,(11)(12)(13)(14)(15)(16)(17).Signal intensity in images acquired with SSFP sequences relies on T2/T1 ratio and does not depend on inflow...

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Image Analysismentioning

confidence: 99%

Assessment of left ventricular function by breath‐hold cine MR imaging: Comparison of different steady‐state free precession sequences

Kunz

Oellig

Krummenauer

et al. 2005

Magnetic Resonance Imaging

View full text Add to dashboard Cite

show abstract

“…Planning variability is due to the positional variation and angular deviation of the imaging planes from the optimum, and is prominent only in automated CMR planning. Intraobserver variability (11)(12)(13)16,36,37) arises due to subjectivity in myocardial border tracing by the human observer. The decomposition of the total variation showed that the relative contribution of the interstudy variability factors was significantly larger than that of the intraobserver factor for all CMR measurements (Fig.…”

Section: Discussionmentioning

confidence: 99%

“…A few steps have been taken in this direction. For example, recently introduced breath-hold imaging with segmented k-space (7,(11)(12)(13)(14) or steadystate (2,11,15,16) techniques has improved the image quality and shortened the examination time up to 10 -15 minutes. However, CMR planning is still performed manually in the clinical environment.…”

mentioning

confidence: 99%

See 1 more Smart Citation

Influence of positional and angular variation of automatically planned short‐axis stacks on quantification of left ventricular dimensions and function with cardiovascular magnetic resonance

Danilouchkine

Geest

Westenberg

et al. 2005

Magnetic Resonance Imaging

View full text Add to dashboard Cite

Purpose: To theoretically and experimentally investigate the influence of the automated cardiovascular magnetic resonance (CMR) scan planning pitfalls, namely inaccurate positioning and tilting of short-axis (SA) imaging planes, on quantification of the left ventricular (LV) dimensions and function. Materials and Methods:Eleven healthy subjects and eight patients underwent CMR. Manually and automatically planned SA sets were acquired. To obtain the quantitative measurements of LV function, one observer performed image analysis twice. The agreement between planning methods, as well as the decomposition of the total variation into interstudy and intraobserver components was measured. Results:The decomposition of the total variation showed that the interstudy factor accounts for 70 -85% of the total variation, while the rest is due to the intraobserver factor. Moreover, the relative contribution of the interstudy factor remains independent from errors in slice positioning and small angular deviation of SA stacks from the optimal orientation. Good agreement between the theoretical and measured variability factors was observed. Conclusion:Global LV function derived from the automatically planned CMR acquisitions yield accurate quantification of the human cardiovascular system. Inaccurate positioning and tilting of SA images does not affect the quantitative measurements of LV function. The computeraided system for automated CMR has proven clinical applicability.

show abstract

Cardiac Tissue Characterization and the Diagnostic Value of Cardiovascular Magnetic Resonance in Systemic Connective Tissue Diseases

Mavrogeni

Sfikakis²,

Gialafos

et al. 2013

Arthritis Care & Research

View full text Add to dashboard Cite

Objective. Accurate diagnosis of cardiovascular involvement in connective tissue diseases (CTDs) remains challenging. We hypothesized that cardiovascular magnetic resonance (CMR) demonstrates cardiac lesions in symptomatic CTD patients with normal echocardiography. Methods. CMR from 246 CTD patients with typical cardiac symptoms (TCS; n ‫؍‬ 146, group A) or atypical cardiac symptoms (ATCS; n ‫؍‬ 100, group B) was retrospectively evaluated. Group A included 9 patients with inflammatory myopathy (IM), 35 with sarcoidosis, 30 with systemic sclerosis (SSc), 14 with systemic lupus erythematosus (SLE), 10 with rheumatoid arthritis (RA), and 48 with small vessel vasculitis. Group B included 25 patients with RA, 20 with SLE, 20 with sarcoidosis, 15 with SSc, 10 with IM, and 10 with small vessel vasculitis. CMR was performed by 1.5T; left ventricular ejection fraction, T2 ratio (edema imaging), and late gadolinium enhancement (LGE; fibrosis imaging) were evaluated. Acute and chronic lesions were characterized as LGE positive plus T2 ratio >2 and T2 ratio <2, respectively. According to LGE, lesions were characterized as diffuse subendocardial, subepicardial, and subendocardial/transmural due to vasculitis, myocarditis, and myocardial infarction, respectively. A stress study by dobutamine echocardiography or stress, nuclear, or adenosine CMR was performed in CTD patients with negative rest CMR. Results. Abnormal CMR was identified in 32% (27% chronic) and 15% (12% chronic) of patients with TCS and ATCS, respectively. Lesions due to vasculitis, myocarditis, and myocardial infarction were evident in 27.4%, 62.6%, and 9.6% of CTD patients, respectively. Stress studies in CTD patients with negative CMR revealed coronary artery disease in 20%. Conclusion. CMR in symptomatic CTD patients with normal echocardiography can assess disease acuity and identify vasculitis, myocarditis, and myocardial infarction.

show abstract

Comparison of magnetic resonance real-time imaging of left ventricular function with conventional magnetic resonance imaging and echocardiography

Cited by 104 publications

References 18 publications

Assessment of left ventricular function by breath‐hold cine MR imaging: Comparison of different steady‐state free precession sequences

Assessment of left ventricular function by breath‐hold cine MR imaging: Comparison of different steady‐state free precession sequences

Influence of positional and angular variation of automatically planned short‐axis stacks on quantification of left ventricular dimensions and function with cardiovascular magnetic resonance

Cardiac Tissue Characterization and the Diagnostic Value of Cardiovascular Magnetic Resonance in Systemic Connective Tissue Diseases

Contact Info

Product

Resources

About