Comparison of Metal Stenting with Radiofrequency Ablation Versus Stenting Alone for Treating Malignant Biliary Strictures: Is There an Added Benefit?

Sharaiha, Reem Z.; Natov, Nikola; Glockenberg, Kati; Widmer, Jessica L.; Gaidhane, Monica; Kahaleh, Michel

doi:10.1007/s10620-014-3264-6

Cited by 123 publications

(118 citation statements)

References 15 publications

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“…The addition of RFA could prove beneficial to such patients, as a recent retrospective study comparing metal stenting with and without RFA showed (8). The study demonstrated that RFA was an independent predictor of survival in the treatment of malignant biliary strictures.…”

Section: A B C D F E Discussionmentioning

confidence: 92%

Biliary tract perforation following percutaneous endobiliary radiofrequency ablation: A report of two cases

et al. 2016

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Abstract. Endobiliary radiofrequency ablation (RFA) has recently been recognized as a beneficial treatment option for malignant biliary obstruction using percutaneous or endoscopic approaches. The feasibility and safety of this method has been demonstrated in clinical studies, with pain, cholangitis and asymptomatic biochemical pancreatitis reported as relatively common complications. By contrast, hepatic coma, newly diagnosed left bundle branch block and partial liver infarction have been reported as uncommon complications. Biliary tract perforation is a serious potential complication of percutaneous intraductal RFA, which may result in severe infection, peritonitis or even mortality, and which has not been previously reported in clinical research. The current study presents the first reports of biliary tract perforation in two patients with unresectable malignant biliary obstruction following percutaneous intraductal RFA. Although the patient in case 1 succumbed 12 days after RFA, the minor biliary tract perforation in case 2 was successfully treated by the deployment of a self-expanding metal stent. This study demonstrates that biliary tract perforation should be recognized as a serious potential complication of endobiliary RFA, and that metal stent deployment should be considered as a treatment option for minor biliary tract perforation.

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Section: A B C D F E Discussionmentioning

confidence: 92%

Biliary tract perforation following percutaneous endobiliary radiofrequency ablation: A report of two cases

et al. 2016

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“…Randomised studies comparing photodynamic therapy combined with biliary stenting to stenting alone have been inconsistent in showing a benefit in terms of patient survival and stent patency 37–39. Retrospective series of patients with inoperable malignant strictures have reported superior patient survival in those who had undergone radiofrequency ablation and stent placement compared with stenting alone;40 41 the results of ongoing randomised trials are keenly awaited.…”

Section: Endoscopic Therapymentioning

confidence: 99%

Endoscopic assessment and management of biliary strictures

Dawwas

Oppong

Webster

2015

Frontline Gastroenterol

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“…20 RFA achieves localized tumor necrosis via thermal energy and can be performed through an endobiliary and percutaneous intraductal technique. The RFA catheter (Habib Endo HPB; EMcision Ltd, London, UK) is a single-use, bipolar device used for endoluminal delivery of RFA into the biliary tree over a 0.035-inch guide wire.…”

Section: Technique/proceduresmentioning

confidence: 99%