Comparison of Microecological Intestinal Indices in Children With Different Value of Body Mass Index

Background. Obesity is a multifactorial disease that is one of the important public health problems in the 21st century. Functional bowel disorders in obese children and adolescents are one of the most common pathologies of the digestive tract. The aim: to characterize the bacteriological composition of the colon microbiota in obese adolescents and identify its associations with the clinical manifestations of functional bowel disorders.Materials and methods. The study included 20 adolescents aged 11–17 years. Stool consistency was assessed using the Bristol Stool Scale. The study of biological material was carried out using standard bacteriological methods. To assess the strength of the relationship between the nominal variables, Cramer’s V test was used.Results. It has been shown that in adolescents with obesity and functional bowel disorders, there is a decrease in the number of representatives of bifidoflora, an increase in the microbial density of Escherichia coli with altered enzymatic properties and an excessive growth of potentially pathogenic enterobacteria. In obese adolescents with functional bowel disorders, abdominal pain associated with the act of defecation is associated with the presence of enterobacteria and E. coli with altered enzymatic properties. Rare bowel movements are associated with an increased abundance of Enterococcus spp. and the presence of opportunistic Enterobacteriaceae microorganisms. Frequent bowel movements are associated with the presence of E. coli with altered enzymatic properties and Clostridium spp. In the presence of loose stool, Clostridium spp. is present; unstable stool (alternation of hard and liquid stools in one patient) is associated with a decrease in the number of lactobacilli and E. coli with normal enzymatic properties, the appearance of E. coli with altered enzymatic properties, opportunistic microorganisms of Enterobacteriaceae family and Clostridium spp. Conclusion. The relationship between the clinical symptoms of functional bowel disorders and changes in the composition of the gut microbiota in obese adolescents may be a justification for conducting in-depth studies aimed at finding early predictors of functional bowel diseases associated with obesity in the adult cohort.

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Associations of clinical features of functional bowel disorders with gut microbiota characteristics in adolescents: A pilot study

Romanitsa

Nemchenko

Pogodina

et al. 2021

Acta biomedica scientifica

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The Role of Streptococcus Mitis and Streptococcus Viridans in the Development of Infectious Diseases (Review)

ЖИЖИЛА¹,

БАЙГАЛИЕВ²,

Burumbayeva³

et al. 2023

Vestnik

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В данной статье представленобзор научной литературы, содержащий актуальные данные об особенностях современных клинико-лабораторных методов идентификации возбудителей инфекционных заболеваний на примере Streptococcus viridans и Streptococcus mitis, представителей условно-патогенной микрофлоры полости рта. Описаны механизмы трансформации данных возбудителей из факультативного комменсализма в вирулентные штаммы. Указаны зарегистрированные случаи возникновения инфекционных заболеваний органов и систем организма человека, возбудителями которых являлись Streptococcus mitis и Streptococcus viridans. Бұл мақалада ауызша шартты патогендік микрофлораның өкілдері Streptococcus viridans және Streptococcus mitis мысалында жұқпалы аурулардың қоздырғыштарын анықтаудың заманауи клиникалық және зертханалық әдістерінің ерекшеліктері туралы өзекті деректерді қамтитын ғылыми әдебиеттерге шолу берілген. Бұл қоздырғыштардың факультативті комменсализмнен вирулентті штамдарға айналу механизмдері сипатталған. Қоздырғыштары Streptococcus mitis және Streptococcus viridans болып табылатын адам ағзасының органдары мен жүйелерінің жұқпалы ауруларының пайда болуының тіркелген жағдайлары көрсетілген. This article presents a review of the scientific literature containing up-to-date data on the features of modern clinical and laboratory methods for identifying pathogens of infectious diseases on the example of Streptococcus viridans and Streptococcus mitis, representatives of the conditionally pathogenic microflora of the oral cavity. The mechanisms of transformation of these pathogens from optional commensalism into virulent strains are described. There are registered cases of infectious diseases of organs and systems of the human body, the causative agents of which were Streptococcus mitis and Streptococcus viridans.

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Comparison of Microecological Intestinal Indices in Children With Different Value of Body Mass Index

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Associations of clinical features of functional bowel disorders with gut microbiota characteristics in adolescents: A pilot study

Associations of clinical features of functional bowel disorders with gut microbiota characteristics in adolescents: A pilot study

The Role of Streptococcus Mitis and Streptococcus Viridans in the Development of Infectious Diseases (Review)

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