Comparison of Minimally and More Invasive Methods of Determining Mixed Venous Oxygen Saturation

Smit, Marli; Levin, Andrew; Coetzee, J. F.

doi:10.1053/j.jvca.2015.09.008

Cited by 2 publications

(1 citation statement)

References 69 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Therefore several studies are ongoing to modifying each step. In this study we point to perform a basic study to challenge the possibility of replacing the CVP with less invasive parameters 12, 13. Based on our findings, there was a significant statistical correlation between some of the VBG parameters including pH and HCO3 and also AG with CVP.…”

Section: Discussionmentioning

confidence: 66%

Correlation of central venous pressure with venous blood gas analysis parameters; a diagnostic study

Rahim-Taleghani

Fatemi

Moghaddam

et al. 2017

Turkish Journal of Emergency Medicine

View full text Add to dashboard Cite

ObjectiveThis study was conducted to assess the correlation between central venous pressure (CVP) and venous blood gas (VBG) analysis parameters, to facilitate management of severe sepsis and septic shock in emergency department.Material and methodsThis diagnostic study was conducted from January 2014 until June 2015 in three major educational medical centers, Tehran, Iran. For patients selected with diagnosis of septic shock, peripheral blood sample was taken for testing the VBG parameters and the anion gap (AG) was calculated. All the mentioned parameters were measured again after infusion of 500 cc of normal saline 0.9% in about 1 h.ResultsTotally, 93 patients with septic shock were enrolled, 63 male and 30 female. The mean age was 72.53 ± 13.03 and the mean Shock Index (SI) before fluid therapy was 0.79 ± 0.30. AG and pH showed significant negative correlations with CVP, While HCO3 showed a significant positive correlation with CVP. These relations can be affected by the treatment modalities used in shock management such as fluid therapy, mechanical ventilation and vasopressor treatment.ConclusionIt is likely that there is a significant statistical correlation between VBG parameters and AG with CVP, but further research is needed before implementation of the results of this study.

show abstract

Section: Discussionmentioning

confidence: 66%

Correlation of central venous pressure with venous blood gas analysis parameters; a diagnostic study

Rahim-Taleghani

Fatemi

Moghaddam

et al. 2017

Turkish Journal of Emergency Medicine

View full text Add to dashboard Cite

show abstract

Novel noninvasive estimation of mixed venous oxygen saturation by echocardiography and expired gas analysis

Onoue

Iwataki

Araki

et al. 2020

American Journal of Physiology-Heart and Circulatory Physiology

View full text Add to dashboard Cite

Mixed venous oxygen (O2) saturation (SvO2) is an important measure to evaluate sufficiency of cardiac output (CO) relative to whole body O2 consumption (VO2), while clinical utilization is limited for required invasive catheterization. By Fick's equation, VO2 (ml/min) = CO (L/min) x Hb (g/dL) x 1.36 (ml/g) x (SaO2 - SvO2) / 10 [Hb = hemoglobin concentration, SaO2 = arterial blood O2 saturation]. Since VO2, CO, Hb and SaO2 can be measured noninvasively with expired gas analysis, echocardiography, simple blood test and percutaneous O2 saturation, SvO2 can be noninvasively calculated. We hypothesized that noninvasively calculated SvO2 shows significant correlation and agrees well with invasively measured SvO2. In 47 patients (29 men, mean age 70±12 years), SvO2 was directly measured by sampling pulmonary artery blood. Calculated SvO2 was also obtained by the method described above. Calculated SvO2 was significantly correlated with measured SvO2 (r = 0.79, P < 0.001) and significantly smaller than measured SvO2 (70±5.1 vs 72.1±4.9%, p < 0.001). Bias at SvO2 was -2.2% (95% confidence interval, -3.2 to -1.1%) with limits of agreement from -9.5 to 5.2%, demonstrating acceptable agreement. The optimal cut-offs values of calculated SvO2 was < 69% for reduced measured SvO2 < 70% with the area under the curve of 0.94. Reduced calculated SvO2 < 69% indicated a sensitivity of 92.9% and specificity of 90.9% for reduced measured SvO2. Noninvasively calculated SvO2 significantly correlated and agreed well with directly measured SvO2. This novel method allows practical evaluation of SvO2 to assess sufficiency of CO according to VO2.

show abstract

Comparison of Minimally and More Invasive Methods of Determining Mixed Venous Oxygen Saturation

Cited by 2 publications

References 69 publications

Correlation of central venous pressure with venous blood gas analysis parameters; a diagnostic study

Correlation of central venous pressure with venous blood gas analysis parameters; a diagnostic study

Novel noninvasive estimation of mixed venous oxygen saturation by echocardiography and expired gas analysis

Contact Info

Product

Resources

About