Comparison of Myocardial Perfusion Imaging Between the New High-Speed Gamma Camera and the Standard Anger Camera

Combined Supine and Prone Myocardial Perfusion Single-Photon Emission Computed Tomography With a Cadmium Zinc Telluride Camera for Detection of Coronary Artery Disease

“…Extra-cardiac activity was significantly less commonly observed in the stress prone vs. supine images (1.10±0.32 vs. 1.32±0.57, Hemodynamic Response to ATP ATP is a precursor of adenosine and its hyperemic effect is thought to be equivalent to its degradation product, adenosine. 11, 12 In all patients, ATP infusion caused some increase in heart rate and some decrease in SBP and diastolic BP (DBP). The baseline heart rate was significantly increased from 65.2±10.5 beats/min to 75.0±11.9 beats/min during ATP infusion (P<0.0001).…”

Clinical Feasibility of Simultaneous Acquisition Rest ^99mTc/Stress ²⁰¹Tl Dual-Isotope Myocardial Perfusion Single-Photon Emission Computed Tomography With Semiconductor Camera

“…The CZT gamma camera is also expected to improve image contrast, provide multi-isotope imaging, faster scan and short acquisition time. 9 A novel dedicated cardiac scanner, the D-SPECT (Spectrum Dynamics, Caesarea, Israel), has 9 CZT detectors (40×160 mm) with square-hole tungsten collimators. In our previous experiment, D-SPECT had 1.6-and 1.4-fold better full width at half maximum (FWHM) in both 99 m Tc and 201 Tl line-sources than the conventional anger gamma camera, respectively.…”

Prognostic value of the cadmium-zinc-telluride camera: A comparison with a conventional (Anger) camera

“…Combined with a stationary array of pinhole detectors focused on the heart, resulting in a threefoldto-fourfold increase in SPECT volume sensitivity, 12 this allows for the opportunity to lower injected activity (patient dose) without sacrificing image quality. [13][14][15] Previous studies have shown good concordance with existing SPECT technology 16,17 and coronary angiography, 12,18 with some evidence of superiority in the obese 16 due to increased counts; examinations of prognostic value have demonstrated an association between all-cause mortality and total perfusion abnormality. 19 We therefore hypothesized that CZT and conventional cameras would prognosticate equally, given differences in baseline clinical characteristics.…”