Comparison of Nd

Abstract

The aim of the study is to compare Nd:YAG capsulotomy rate between acrylic 1- and 3-piece intraocular lenses. Among 924 eyes of 762 patients who received cataract surgery, we selected the 303 patients (404 eyes) implanted with an SN60WF 1-piece intraocular lens (Alcon, Fort Worth, TX) or a YA-60BBR 3-piece intraocular lens (Hoya Co., Tokyo, Japan). For intraindividual comparison, we enrolled the 17 patients implanted with an SN60WF in 1 eye and a YA-60BBR in the contralateral eye. We compared Nd:YAG capsulotomy rate between acrylic 1- and 3-piece intraocular lenses 24 months after the operation. Of the 404 eyes in this study, Nd:YAG capsulotomy was performed in 20 of 268 eyes (7.5%) in the SN60WF 1-piece intraocular lens group and 24 of 136 eyes (17.6%) in the YA-60BBR 3-piece intraocular lens group; the difference was statistically significant (P = .002). Among the 17 patients (34 eyes) who were implanted with 2 different inraocular lenses, Nd:YAG capsulotomy was performed in only 2 eyes (12%) in the SN60WF group and 9 eyes (53%) in the YA-60BBR group; the difference was statistically significant (P = .020).The authors found a significantly greater incidence of Nd:YAG capsulotomy in eyes who received 3-piece lenses compared with those who received 1-piece lenses.

Arginase-1 promotes lens epithelial-to-mesenchymal transition in different models of anterior subcapsular cataract

“…Fibrotic opacities induced by trauma, inflammation, or radiation can accumulate underneath the anterior lens capsule, causing ASC [ 3 ]. PCO is one of the most common complications of phacoemulsification with intraocular lens (IOL) implantation [ 4 ], mostly occurring soon to a few years after cataract surgery [ 5 , 6 ], with a high incidence in young patients [ 7 ]. After cataract surgery, residual LECs in the anterior and equatorial regions proliferate, migrate, transform into a myofibroblastic phenotype and secrete excessive extracellular matrix proteins on the posterior capsule, leading to PCO [ 8 , 9 ].…”