Comparison of Neointimal Coverage of Sirolimus-Eluting Stents and Paclitaxel-Eluting Stents Using Optical Coherence Tomography at 9 Months After Implantation

Kim, Jin Sun; Kim, Jung Sun; Kim, Tae Hoon; Chen, Fan; Lee, Jung Myung; Kim, Woong; Ko, Young Guk; Choi, Donghoon; Hong, Myeong Ki; Jang, Yangsoo

doi:10.1253/circj.cj-09-0546

Cited by 54 publications

(39 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…6,7 Our findings are in accordance with those reports, showing greater neointimal proliferation in stents with PLIA than in stents without PLIA, for both DES and BMS. In contrast to a human study, 8 SES showed numerically greater %NIA than PES in this porcine model. Interestingly, SES also showed a numerically higher incidence of PLIA than PES, with a greater prevalence of struts with PLIA.…”

Section: Peri-strut Low Intensity Area On Octcontrasting

confidence: 99%

Intriguing Peri-Strut Low-Intensity Area Detected by Optical Coherence Tomography After Coronary Stent Deployment

Teramoto

Ikeno

Otake

et al. 2010

Circ J

View full text Add to dashboard Cite

Section: Peri-strut Low Intensity Area On Octcontrasting

confidence: 99%

Intriguing Peri-Strut Low-Intensity Area Detected by Optical Coherence Tomography After Coronary Stent Deployment

Teramoto

Ikeno

Otake

et al. 2010

Circ J

View full text Add to dashboard Cite

“…Vessel healing, such as neointimal proliferation after stent implantation, was different even among different types of DES. 33, 34 This difference might affect the natural course of ISA development. In addition, IVUS-detected ISAs, which were bigger than those seen on OCT, were all resolved at follow-up in the present study.…”

Section: Discussionmentioning

confidence: 99%

Natural History of Stent Edge Dissection, Tissue Protrusion and Incomplete Stent Apposition Detectable Only on Optical Coherence Tomography After Stent Implantation

Kume

Okura

Miyamoto

et al. 2012

Circ J

View full text Add to dashboard Cite

“…13 The study by Kim et al found that uncovered struts were frequently observed in SES, but that the pattern of neointima was more heterogeneous in PES at 9 months. 14 Postmortem studies performed by Farb et al showed that LST could be associated with impaired healing and the absence of full neointimal coverage over struts at branchpoint ostia. 5 In the present study, we did not observe LST at the bifurcation site in any patient, even though these branch points are foci of low shear and low-flow velocity and thus predisposed to thrombus development.…”

Section: Discussionmentioning

confidence: 99%

Assessment by Optical Coherence Tomography of Stent Struts Across Side Branch

Liu

Imanishi

Kubo

et al. 2011

Circ J

View full text Add to dashboard Cite

Background: Late stent thrombosis (LST) after drug-eluting stent (DES) implantation is a major clinical problem that has not been fully explained. Incomplete neointimal coverage of stent struts is an important morphometric predictor of LST, which may be associated with impaired healing and the absence of full coverage of struts at branch-point ostia. Optical coherence tomography (OCT) was performed to compare 3 types of stents placed across side branches. Methods and Results:At 9-month follow-up, the neointimal coverage of the struts of 58 stents across a side branch was measured by OCT (bare metal (BMS), n=20; sirolimus-eluting (SES), n=23; paclitaxel-eluting (PES), n=15). According to the diameter ratio of side branch to main vessel, the side branches were classified as either large (ratio >0.33) or small (ratio ≤0.33). BMS had the lowest frequency of uncovered struts (29.4%) and the greatest neointimal thickness on the struts (123±33 μm). Neointimal thickness on the struts was less for SES than for PES (72±16 vs. 91±22 μm, P=0.009), but there was no difference in the frequency of uncovered struts (66.1% vs. 58.6%, P=0.493). For large side branches, the frequency of uncovered struts was greater than in the small group for SES (87.5% vs. 40.7%, P=0.0002) and PES (83.3% vs. 18.2%; P=0.0013); there was no significant difference for BMS (43.8% vs. 16.7%, P=0.138). Conclusions:Neointimal coverage on struts across a side branch was less frequently observed in DES than in BMS, particularly in large side branches. (Circ J 2011; 75: 106 - 112)

show abstract

Comparison of Neointimal Coverage of Sirolimus-Eluting Stents and Paclitaxel-Eluting Stents Using Optical Coherence Tomography at 9 Months After Implantation

Cited by 54 publications

References 32 publications

Intriguing Peri-Strut Low-Intensity Area Detected by Optical Coherence Tomography After Coronary Stent Deployment

Intriguing Peri-Strut Low-Intensity Area Detected by Optical Coherence Tomography After Coronary Stent Deployment

Natural History of Stent Edge Dissection, Tissue Protrusion and Incomplete Stent Apposition Detectable Only on Optical Coherence Tomography After Stent Implantation

Assessment by Optical Coherence Tomography of Stent Struts Across Side Branch

Contact Info

Product

Resources

About