This study considers the usage of multilinear regression and artificial neural network modelling to forecast ozone concentrations with regard to weather-related indicators (wind speed, wind direction, relative humidity and temperature). Initial data were obtained by measuring the meteorological parameters using the PC Radio Weather Station. Ozone concentrations near high-voltage lines were measured using RS1003 and at a 220 m distance using ML9811. Neural network models such as the multilayer perceptron and radial basis function neural networks were constructed. The prognostic capacities of the designed models were assessed by comparing the result data by way of the square of the coefficient of multiple correlations (R2) and mean square error (MSE) values. The number of hidden neurons was optimised by decreasing an error function that recorded the number of units in the hidden layers to the precision of the expanded networks. The neural software IBM SPSS 26v was used for artificial neural network (ANN) modelling. The study demonstrated that the linear regression modelling approach was lacking in its capacity to predict the investigated ozone concentrations by used parameters, whereas the use of an ANN offered more precise outcomes. The conducted tests’ results established the strength of the designed artificial neural network models with irrelevant differences between detected and forecasted data.